Detail Information for IndEnz0005000131
IED ID IndEnz0005000131
Enzyme Type ID lipase000131
Protein Name Lipase ZK262.3
EC 3.1.1.-
Gene Name ZK262.3
Organism Caenorhabditis elegans
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans
Enzyme Sequence MPKNLRFSVFLLFLLCINSVFGEFGPEDAQYNETEARMLLSLSAAAYSLDVTPCIGRTFSPAENQTLLSTFSVRCDFVGNPCAGYIVVSDVLQQITVVFRGTKTSSQLLLEGWTTLKPSSDFYGMGLVNTYFRSGHEKTWQYVQDALSISQYRNYDVYVTGHSLGGALAGLCAPRIVHDGLRQSQKIKVVTFGEPRVGNIEFSRAYDQLVPYSFRVVHSGDVVPHLPGCVKDLSYTPPAGSDGSMPCDPVSTNGGYHHAIEIWYPGNMTQGDPFMVCTGLPRDEDFGCSDSLKVNLGDTNQGVWDHRNYFGVEVPDFGKGGCDPSMTFKGPPTKTGVLSLVGSVFGRKRRSIR
Enzyme Length 353
Uniprot Accession Number Q9XTR8
Absorption
Active Site ACT_SITE 163; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 221; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU10037; ACT_SITE 306; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU10037
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.1.1.-
Enzyme Function FUNCTION: Probable lipase. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Disulfide bond (1); Glycosylation (3); Signal peptide (1)
Keywords Disulfide bond;Glycoprotein;Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..22; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 10778742; 20439776; 21367940; 22267497; 22286215; 22560298; 23800452; 24884423; 25487147; 6593563;
Motif
Gene Encoded By
Mass 38,743
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda