| IED ID | IndEnz0005000137 |
| Enzyme Type ID | lipase000137 |
| Protein Name |
Lipase 1 EC 3.1.1.3 Triacylglycerol lipase |
| Gene Name | lip1 L1 |
| Organism | Moraxella sp. (strain TA144) |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Moraxellales Moraxellaceae Moraxella unclassified Moraxella Moraxella sp. (strain TA144) |
| Enzyme Sequence | MFIMIKKSELAKAIIVTGALVFSIPTLAEVTLSETTVSSIKSEATVSSTKKALPATPSDCIADSKITAVALSDTRDNGPFSIRTKRISRQSAKGFGGGTIHYPTNASGCGLLGAIAVVPGYVSYENSIKWWGPRLASWGFVVITINTNSIYDDPDSRAAQLNAALDNMIADDTVGSMIDPKRLGAIGWSMGGGGALKLATERSTVRAIMPLAPYHDKSYGEVKTPTLVIACEDDRIAETKKYANAFYKNAIGPKMKVEVNNGSHFCPSYRFNEILLSKPGIAWMQRYINNDTRFDKFLCANENYSKSPRISAYDYKDCP |
| Enzyme Length | 319 |
| Uniprot Accession Number | P19833 |
| Absorption | |
| Active Site | ACT_SITE 189; /note=Nucleophile; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+); Xref=Rhea:RHEA:12044, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17855, ChEBI:CHEBI:18035, ChEBI:CHEBI:28868; EC=3.1.1.3; |
| DNA Binding | |
| EC Number | 3.1.1.3 |
| Enzyme Function | |
| Temperature Dependency | BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Active at temperatures close to 0 degree Celsius.; |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Metal binding (2) |
| Keywords | Calcium;Hydrolase;Lipid degradation;Lipid metabolism;Metal-binding |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 34,624 |
| Kinetics | |
| Metal Binding | METAL 314; /note=Calcium; /evidence=ECO:0000250; METAL 317; /note=Calcium; /evidence=ECO:0000250 |
| Rhea ID | RHEA:12044 |
| Cross Reference Brenda |