Detail Information for IndEnz0005000165
IED ID IndEnz0005000165
Enzyme Type ID lipase000165
Protein Name Lipase 3
EC 3.1.1.3
Gene Name LIP3
Organism Candida albicans (Yeast)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Debaryomycetaceae Candida/Lodderomyces clade Candida Candida albicans (Yeast)
Enzyme Sequence MKTLVVLCTLLSIIFASPLSLKSPLVDDFYNPPRGYESAKLGEILKLRKTPGKISSLFIPVEVKNSWQLLVRSEDSFGNAAAIVTTVIEPFNADPSKVVSYQSWEDAANIECSPSYGMQFGAPLSSVQTQVDMIFIVPLLDKGCFVVLPDYEGPKSTFGVGRQSGKATLDSIKAVLKTKDFSGINDDAQVAMWGYSGGTIAAGWAATLQPKYAQELKKNLIGAALGGFVINITATAEATDGTLFAGLIPNALNGLANEFPDFKKRMYEVVEKRYEGALQQGTQHCLGGAILHFAFDQVFTGDHRYFEQGYGLLEEEVFNRTISGNSLLYMDQEYLPDIPIFVYHGSLDGIVPIPDVHGVYKNWCDWGIDSFEFAEDSLNGHLTEIVVGAPAAITWLDARFDGQPVVEGCKKTTRITNFSYPNISDSTRNFFKGILDSLTASQLGPGVTSDNVTLSGLTGFMGGLSKFKKSV
Enzyme Length 471
Uniprot Accession Number Q9P8W2
Absorption
Active Site ACT_SITE 196; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 344; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=a triacylglycerol + H2O = a diacylglycerol + a fatty acid + H(+); Xref=Rhea:RHEA:12044, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17855, ChEBI:CHEBI:18035, ChEBI:CHEBI:28868; EC=3.1.1.3;
DNA Binding
EC Number 3.1.1.3
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Glycosylation (5); Signal peptide (1)
Keywords Glycoprotein;Hydrolase;Lipid degradation;Lipid metabolism;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:11131027}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..16; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 51,226
Kinetics
Metal Binding
Rhea ID RHEA:12044
Cross Reference Brenda