| IED ID | IndEnz0005000247 |
| Enzyme Type ID | lipase000247 |
| Protein Name |
Lipase-specific foldase Lif Lipase activator protein Lipase chaperone Lipase helper protein Lipase modulator |
| Gene Name | lifO lipB |
| Organism | Burkholderia plantarii |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Betaproteobacteria Burkholderiales Burkholderiaceae Burkholderia Burkholderia plantarii |
| Enzyme Sequence | MAQADRPARGGLAARPMRGASFALAGLVACAACAAVVLWLRPAAPSPAPAGAVAGGPAAGVPAAASGAAEAAMPLPAALPGALAGSHAPRLPLAAGGRLARTRAVREFFDYCLTAQGELTPAALDALVRREIAAQLDGSPAQAEALGVWRRYRAYFDALAQLPGDGAVLGDKLDPAAMQLALDQRAALADRTLGEWAEPFFGDEQRRQRHDLERIRIANDTTLSPEQKAARLAALDAQLTPDERAQQAALHAQQDAVTKIADLQKAGATPDQMRAQIAQTLGPEAAARAAQMQQDDEAWQTRYQAYAAERDRIAAQGLAPQDRDARIAQLRQQTFTAPGEAIRAASLDRGAGG |
| Enzyme Length | 353 |
| Uniprot Accession Number | Q05490 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Involved in the folding of the extracellular lipase (lip) during its passage through the periplasm. {ECO:0000269|PubMed:8412705, ECO:0000305|PubMed:8412704}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (2); Chain (1); Helix (13); Topological domain (2); Transmembrane (1); Turn (1) |
| Keywords | 3D-structure;Cell inner membrane;Cell membrane;Chaperone;Lipid degradation;Lipid metabolism;Membrane;Transmembrane;Transmembrane helix |
| Interact With | P0DUB8 |
| Induction | INDUCTION: By growth on olive oil or oleic acid; part of the lip-lifO (also called lipA-lipB) operon. {ECO:0000269|PubMed:8412704}. |
| Subcellular Location | SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000269|PubMed:8412704}; Single-pass membrane protein {ECO:0000305|PubMed:8412704}; Periplasmic side {ECO:0000305|PubMed:8412704}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 2ES4; |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 36,831 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |