| IED ID |
IndEnz0005000262 |
| Enzyme Type ID |
lipase000262 |
| Protein Name |
Glutactin
|
| Gene Name |
Glt CG9280 |
| Organism |
Drosophila melanogaster (Fruit fly) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Hexapoda
Insecta
Dicondylia
Pterygota (winged insects)
Neoptera
Endopterygota
Diptera
Brachycera
Muscomorpha
Eremoneura
Cyclorrhapha
Schizophora
Acalyptratae
Ephydroidea
Drosophilidae (pomace flies)
Drosophilinae
Drosophilini
Drosophila (fruit flies)
Sophophora
melanogaster group
melanogaster subgroup
Drosophila melanogaster (Fruit fly)
|
| Enzyme Sequence |
MKPLLLVLALCGAQVHAHSVGLRPDYNDYSDEDTRRDWLPEPLKPVPWQSETRYAQPQEAVVQAPEVGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQPIGYQGRVNATVQSPNCAQFPELDRLRLSESRGENVDDCLTLDIYAPEGANQLPVLVFVHGEMLFDGGSEEAQPDYVLEKDVLLVSINYRLAPFGFLSALTDELPGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATLAHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINPSAQGLKPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLVVGDPLGFLPSHPASLATNSSLALPMIIGATKDASAFIVSRIYDQLARLQSRNVSDYIDVVLRHTAPPSEHRLWKQWALREIFTPIQEQTASLQTVAPGLLELSNYILYRAPVINSISQSYRSVPAYLYTFDYRGEHHRFGHLSNPLPFGVDASLSDDSVYLFPYPPEASRLNPLDRSLSRALVTMWVNFATTGVPNPSSGVWPQATSEYGPFLRFTNNQQSPLELDPHFGEGIYLPNYRVIYKPTTNFSPPITTTTTTTTTTTTTSRPYAYNPYANWQNRPSQQHPNWHPADPEYVRAQEARQQEFIREREQRRREQQLRDQQRYPQQEPREQQDERIRQQREQEERLRQQREQEERLRQQRELEERIRQQQEREQYEREQQEREQREREELERQQREREQQQPEQQPEYNPEPVNPWGYPVQEPQPDDNPEDGRLPYPSYEQYGPEGNENLPETDANRNFSEEDREQQQQEQLRREQQEQQEREYQLQLEREQQEREQQERGQQEPGPEEYPSYEEYSRALQEKNAERDRIYAEEQERERQQQETLLQENQQHPEQSLPEEQPTHPNYEAYDGDRSYAEEQEREQQRRDQVEQEREEQPDEDQGEEYERSPDEEEAAEQDVLKVEDFPSYEAYLEAATKLREEQEEQEKLEEERYRAQQEEEDRIQAERERNSRN |
| Enzyme Length |
1026 |
| Uniprot Accession Number |
P33438 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Not known. Binds calcium ions. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (8); Disulfide bond (2); Glycosylation (4); Modified residue (15); Region (3); Sequence conflict (2); Signal peptide (1) |
| Keywords |
Basement membrane;Calcium;Direct protein sequencing;Disulfide bond;Extracellular matrix;Glycoprotein;Reference proteome;Secreted;Signal;Sulfation |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix, basement membrane. |
| Modified Residue |
MOD_RES 26; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 29; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 182; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 559; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 645; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 727; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 836; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 862; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 865; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 868; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 922; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 928; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 981; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 984; /note=Sulfotyrosine; /evidence=ECO:0000255; MOD_RES 1006; /note=Sulfotyrosine; /evidence=ECO:0000255 |
| Post Translational Modification |
PTM: Extensively O-glycosylated and also N-glycosylated.; PTM: About four tyrosines are sulfated. {ECO:0000269|PubMed:2108864}. |
| Signal Peptide |
SIGNAL 1..17 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
10628989;
10705444;
10864456;
11900973;
12417656;
14605208;
14630943;
15525669;
15710747;
16258543;
16515779;
16580994;
17764943;
18039034;
20220848;
20371351;
20813047;
21074052;
2120047;
21480662;
21688401;
22055292;
22554890;
22586369;
23071443;
23797713;
23850873;
23944235;
23988573;
25193493;
25294943;
25312911;
2557060;
27058248;
27357258;
27582081;
27794539;
29268741;
30002131;
30733377;
30974174;
31367663;
31722958;
31963772;
32598400;
32900993;
33322177;
33573306;
7515725;
7760738;
7821224;
8890157;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
118,749 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|