| IED ID |
IndEnz0005000281 |
| Enzyme Type ID |
lipase000281 |
| Protein Name |
Bacteriocin curvaticin DN317
|
| Gene Name |
|
| Organism |
Latilactobacillus curvatus (Lactobacillus curvatus) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Terrabacteria group
Firmicutes
Bacilli
Lactobacillales
Lactobacillaceae
Latilactobacillus
Latilactobacillus curvatus (Lactobacillus curvatus)
|
| Enzyme Sequence |
IPYGGNGVHHGKAGDSXTVDTAIGNIGNNAASIIGGMISGWASGLAG |
| Enzyme Length |
47 |
| Uniprot Accession Number |
C0HK82 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Has bactericidal activity against various Gram-negative Campylobacter, and the Gram-positive L.monocytogenes and B.subtilis. In vitro, inhibits C.jejuni strain ATCC 33560 (MIC=27.3 ug/ml). {ECO:0000269|PubMed:27812926}. |
| Temperature Dependency |
BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Thermostable. Retains 100% activity after incubation at 60 degrees Celsius for 60 minutes and 15% after incubation at 121 degrees Celsius for 15 minutes. {ECO:0000269|PubMed:27812926}; |
| PH Dependency |
BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Stable between pH 4.0 and pH 8.0. {ECO:0000269|PubMed:27812926}; |
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1) |
| Keywords |
Antibiotic;Antimicrobial;Bacteriocin;Direct protein sequencing;Secreted |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:27812926}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
4,448 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|