| IED ID | IndEnz0005000429 |
| Enzyme Type ID | lipase000429 |
| Protein Name |
Fatty-acid amide hydrolase 1 EC 3.5.1.99 Anandamide amidohydrolase 1 Fatty acid ester hydrolase EC 3.1.1.- Oleamide hydrolase 1 |
| Gene Name | FAAH FAAH1 |
| Organism | Homo sapiens (Human) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human) |
| Enzyme Sequence | MVQYELWAALPGASGVALACCFVAAAVALRWSGRRTARGAVVRARQRQRAGLENMDRAAQRFRLQNPDLDSEALLALPLPQLVQKLHSRELAPEAVLFTYVGKAWEVNKGTNCVTSYLADCETQLSQAPRQGLLYGVPVSLKECFTYKGQDSTLGLSLNEGVPAECDSVVVHVLKLQGAVPFVHTNVPQSMFSYDCSNPLFGQTVNPWKSSKSPGGSSGGEGALIGSGGSPLGLGTDIGGSIRFPSSFCGICGLKPTGNRLSKSGLKGCVYGQEAVRLSVGPMARDVESLALCLRALLCEDMFRLDPTVPPLPFREEVYTSSQPLRVGYYETDNYTMPSPAMRRAVLETKQSLEAAGHTLVPFLPSNIPHALETLSTGGLFSDGGHTFLQNFKGDFVDPCLGDLVSILKLPQWLKGLLAFLVKPLLPRLSAFLSNMKSRSAGKLWELQHEIEVYRKTVIAQWRALDLDVVLTPMLAPALDLNAPGRATGAVSYTMLYNCLDFPAGVVPVTTVTAEDEAQMEHYRGYFGDIWDKMLQKGMKKSVGLPVAVQCVALPWQEELCLRFMREVERLMTPEKQSS |
| Enzyme Length | 579 |
| Uniprot Accession Number | O00519 |
| Absorption | |
| Active Site | ACT_SITE 142; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 217; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 241; /note=Acyl-ester intermediate; /evidence=ECO:0000250 |
| Activity Regulation | ACTIVITY REGULATION: Inhibited by O-aryl carbamates and alpha-keto heterocycles (PubMed:17015445). Inhibited by trifluoromethyl ketone (PubMed:9122178). {ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:9122178}. |
| Binding Site | BINDING 191; /note=Substrate; via carbonyl oxygen; /evidence=ECO:0000250; BINDING 217; /note=Substrate; /evidence=ECO:0000250 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + ethanolamine; Xref=Rhea:RHEA:26136, ChEBI:CHEBI:2700, ChEBI:CHEBI:15377, ChEBI:CHEBI:32395, ChEBI:CHEBI:57603; EC=3.5.1.99; Evidence={ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:19926788, ECO:0000269|PubMed:9122178};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:26137; Evidence={ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:19926788, ECO:0000269|PubMed:9122178}; CATALYTIC ACTIVITY: Reaction=(9Z)-octadecenamide + H2O = (9Z)-octadecenoate + NH4(+); Xref=Rhea:RHEA:26506, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:30823, ChEBI:CHEBI:116314; EC=3.5.1.99; Evidence={ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:9122178};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:26507; Evidence={ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:9122178}; CATALYTIC ACTIVITY: Reaction=2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycerol + H(+); Xref=Rhea:RHEA:26132, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17754, ChEBI:CHEBI:32395, ChEBI:CHEBI:52392; Evidence={ECO:0000269|PubMed:21049984};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:26133; Evidence={ECO:0000269|PubMed:21049984}; CATALYTIC ACTIVITY: Reaction=H2O + N-(9Z-octadecenoyl) ethanolamine = (9Z)-octadecenoate + ethanolamine; Xref=Rhea:RHEA:45060, ChEBI:CHEBI:15377, ChEBI:CHEBI:30823, ChEBI:CHEBI:57603, ChEBI:CHEBI:71466; Evidence={ECO:0000269|PubMed:17015445};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:45061; Evidence={ECO:0000269|PubMed:17015445}; CATALYTIC ACTIVITY: Reaction=H2O + N-hexadecanoylethanolamine = ethanolamine + hexadecanoate; Xref=Rhea:RHEA:45064, ChEBI:CHEBI:7896, ChEBI:CHEBI:15377, ChEBI:CHEBI:57603, ChEBI:CHEBI:71464; Evidence={ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:19926788};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:45065; Evidence={ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:19926788}; CATALYTIC ACTIVITY: Reaction=H2O + hexadecanamide = hexadecanoate + NH4(+); Xref=Rhea:RHEA:62984, ChEBI:CHEBI:7896, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:74475; Evidence={ECO:0000269|PubMed:9122178};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:62985; Evidence={ECO:0000269|PubMed:9122178}; CATALYTIC ACTIVITY: Reaction=H2O + tetradecamide = NH4(+) + tetradecanoate; Xref=Rhea:RHEA:62992, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:30807, ChEBI:CHEBI:137125; Evidence={ECO:0000269|PubMed:9122178};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:62993; Evidence={ECO:0000269|PubMed:9122178}; CATALYTIC ACTIVITY: Reaction=H2O + N-(9Z-octadecenoyl)-taurine = (9Z)-octadecenoate + taurine; Xref=Rhea:RHEA:63148, ChEBI:CHEBI:15377, ChEBI:CHEBI:30823, ChEBI:CHEBI:146191, ChEBI:CHEBI:507393; Evidence={ECO:0000269|PubMed:17015445};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63149; Evidence={ECO:0000269|PubMed:17015445}; CATALYTIC ACTIVITY: Reaction=(9Z,12Z,15Z)-octadecatrienamide + H2O = (9Z,12Z,15Z)-octadecatrienoate + NH4(+); Xref=Rhea:RHEA:62976, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:32387, ChEBI:CHEBI:142684; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:62977; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(5Z,8Z,11Z,14Z)-eicosatetraenamide + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + NH4(+); Xref=Rhea:RHEA:63016, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:32395, ChEBI:CHEBI:137830; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63017; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(6Z)-octadecenamide + H2O = (6Z)-octadecenoate + NH4(+); Xref=Rhea:RHEA:63008, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:32375, ChEBI:CHEBI:146168; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63009; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(15Z)-tetracosenamide + H2O = (15Z)-tetracosenoate + NH4(+); Xref=Rhea:RHEA:63028, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:32392, ChEBI:CHEBI:146166; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63029; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(8Z,11Z,14Z)-eicosatrienamide + H2O = (8Z,11Z,14Z)-eicosatrienoate + NH4(+); Xref=Rhea:RHEA:62996, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:71589, ChEBI:CHEBI:146163; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:62997; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(11Z,14Z,17Z)-eicosatrienamide + H2O = (11Z,14Z,17Z)-eicosatrienoate + NH4(+); Xref=Rhea:RHEA:63000, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:77223, ChEBI:CHEBI:146164; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63001; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(11Z,14Z)-eicosadienamide + H2O = (11Z,14Z)-eicosadienoate + NH4(+); Xref=Rhea:RHEA:63004, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:77220, ChEBI:CHEBI:146165; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63005; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(9Z,12Z)-octadecadienamide + H2O = (9Z,12Z)-octadecadienoate + NH4(+); Xref=Rhea:RHEA:63020, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:30245, ChEBI:CHEBI:82984; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63021; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=1-O-methyl-(5Z,8Z,11Z,14Z)-eicosatetraenoate + H2O = (5Z,8Z,11Z,14Z)-eicosatetraenoate + H(+) + methanol; Xref=Rhea:RHEA:63052, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:17790, ChEBI:CHEBI:32395, ChEBI:CHEBI:78033; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63053; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=(11Z)-eicosenamide + H2O = (11Z)-eicosenoate + NH4(+); Xref=Rhea:RHEA:63120, ChEBI:CHEBI:15377, ChEBI:CHEBI:28938, ChEBI:CHEBI:32426, ChEBI:CHEBI:146167; Evidence={ECO:0000250|UniProtKB:P97612};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63121; Evidence={ECO:0000250|UniProtKB:P97612}; CATALYTIC ACTIVITY: Reaction=H2O + N-(9Z-hexadecenoyl) ethanolamine = (9Z)-hexadecenoate + ethanolamine; Xref=Rhea:RHEA:35563, ChEBI:CHEBI:15377, ChEBI:CHEBI:32372, ChEBI:CHEBI:57603, ChEBI:CHEBI:71465; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:35564; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-octadecanoyl ethanolamine = ethanolamine + octadecanoate; Xref=Rhea:RHEA:63124, ChEBI:CHEBI:15377, ChEBI:CHEBI:25629, ChEBI:CHEBI:57603, ChEBI:CHEBI:85299; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63125; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-docosanoyl-ethanolamine = docosanoate + ethanolamine; Xref=Rhea:RHEA:63128, ChEBI:CHEBI:15377, ChEBI:CHEBI:23858, ChEBI:CHEBI:57603, ChEBI:CHEBI:146186; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63129; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-tetracosanoyl-taurine = taurine + tetracosanoate; Xref=Rhea:RHEA:63140, ChEBI:CHEBI:15377, ChEBI:CHEBI:31014, ChEBI:CHEBI:132049, ChEBI:CHEBI:507393; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63141; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-(15Z-tetracosenoyl)-ethanolamine = (15Z)-tetracosenoate + ethanolamine; Xref=Rhea:RHEA:63144, ChEBI:CHEBI:15377, ChEBI:CHEBI:32392, ChEBI:CHEBI:57603, ChEBI:CHEBI:146187; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63145; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-docosanoyl-taurine = docosanoate + taurine; Xref=Rhea:RHEA:63156, ChEBI:CHEBI:15377, ChEBI:CHEBI:23858, ChEBI:CHEBI:146196, ChEBI:CHEBI:507393; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63157; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-(15Z-tetracosenoyl)-taurine = (15Z)-tetracosenoate + taurine; Xref=Rhea:RHEA:63160, ChEBI:CHEBI:15377, ChEBI:CHEBI:32392, ChEBI:CHEBI:146198, ChEBI:CHEBI:507393; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63161; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-tricosanoyl-taurine = taurine + tricosanoate; Xref=Rhea:RHEA:63164, ChEBI:CHEBI:15377, ChEBI:CHEBI:79007, ChEBI:CHEBI:146197, ChEBI:CHEBI:507393; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:63165; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=(9Z)-octadecenoate + glycine = H2O + N-(9Z-octadecenoyl)glycine; Xref=Rhea:RHEA:51316, ChEBI:CHEBI:15377, ChEBI:CHEBI:30823, ChEBI:CHEBI:57305, ChEBI:CHEBI:133992; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=right-to-left; Xref=Rhea:RHEA:51318; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-(5Z,8Z,11Z,14Z)-eicosatetraenoyl-glycine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + glycine; Xref=Rhea:RHEA:64108, ChEBI:CHEBI:15377, ChEBI:CHEBI:32395, ChEBI:CHEBI:57305, ChEBI:CHEBI:59002; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:64109; Evidence={ECO:0000250|UniProtKB:O08914}; CATALYTIC ACTIVITY: Reaction=H2O + N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-L-serine = (5Z,8Z,11Z,14Z)-eicosatetraenoate + L-serine; Xref=Rhea:RHEA:64116, ChEBI:CHEBI:15377, ChEBI:CHEBI:32395, ChEBI:CHEBI:33384, ChEBI:CHEBI:149697; Evidence={ECO:0000250|UniProtKB:O08914};PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:64117; Evidence={ECO:0000250|UniProtKB:O08914}; |
| DNA Binding | |
| EC Number | 3.5.1.99; 3.1.1.- |
| Enzyme Function | FUNCTION: Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules (PubMed:9122178, PubMed:17015445, PubMed:19926788). Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates (PubMed:9122178, PubMed:17015445). It can also catalyze the hydrolysis of the endocannabinoid 2-arachidonoylglycerol (2-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-glycerol) (PubMed:21049984). FAAH cooperates with PM20D1 in the hydrolysis of amino acid-conjugated fatty acids such as N-fatty acyl glycine and N-fatty acyl-L-serine, thereby acting as a physiological regulator of specific subsets of intracellular, but not of extracellular, N-fatty acyl amino acids (By similarity). {ECO:0000250|UniProtKB:O08914, ECO:0000269|PubMed:17015445, ECO:0000269|PubMed:19926788, ECO:0000269|PubMed:21049984, ECO:0000269|PubMed:9122178}. |
| Temperature Dependency | |
| PH Dependency | BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is around 9.0. {ECO:0000269|PubMed:17015445}; |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Binding site (2); Chain (1); Intramembrane (1); Modified residue (1); Natural variant (2); Region (1); Sequence conflict (2); Topological domain (2); Transmembrane (1) |
| Keywords | Cytoplasm;Cytoskeleton;Direct protein sequencing;Hydrolase;Lipid degradation;Lipid metabolism;Membrane;Phosphoprotein;Reference proteome;Transmembrane;Transmembrane helix |
| Interact With | Q7Z3S9 |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Endomembrane system {ECO:0000269|PubMed:17015445}; Single-pass membrane protein {ECO:0000269|PubMed:17015445}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:17015445}. Note=Seems to be attached to intracellular membranes and a portion of the cytoskeletal network. |
| Modified Residue | MOD_RES 241; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:24275569 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 11818522; 12008024; 12153574; 12556536; 12799380; 14657172; 15219977; 15721218; 15809662; 17065342; 17216208; 17290447; 17342744; 17449448; 17553686; 17621164; 17712725; 17962356; 17991615; 18068305; 18295974; 18497731; 18566995; 18705688; 18805581; 18819056; 19002671; 19014633; 19053981; 19086053; 19095868; 19103437; 19165169; 19193342; 19419760; 19659925; 19801960; 19859057; 19874574; 19890266; 19913121; 19958092; 20010552; 20010914; 20015515; 20044928; 20054193; 20056290; 20065978; 20080186; 20098695; 20099163; 20102775; 20189896; 20369362; 20628086; 20631561; 20711500; 20716455; 20808855; 20870184; 20976246; 21037510; 21118518; 21442624; 21477106; 21519771; 22035053; 22068813; 22442717; 22609216; 22701012; 22776995; 22826533; 22827915; 22832737; 23122699; 23211960; 23333123; 23347118; 23372171; 23616186; 23926887; 24042479; 24172113; 24223930; 24407958; 24444427; 24445122; 24616451; 24811863; 25270105; 25416956; 25444073; 25456842; 25558980; 25731744; 26036940; 26106535; 26111155; 26561012; 26738935; 26806592; 26808012; 26857901; 26923505; 26930716; 26948343; 27005594; 27074158; 27240888; 27345297; 27346075; 27716956; 28132572; 28150397; 28243972; 28481838; 29652995; 30126012; 30159798; 30291441; 30929760; 31013550; 31286394; 31292037; 31335650; 31377429; 31382124; 31775159; 31789429; 31914367; 32041998; 32398646; 32968163; 33038759; 33460184; 33729738; |
| Motif | |
| Gene Encoded By | |
| Mass | 63,066 |
| Kinetics | BIOPHYSICOCHEMICAL PROPERTIES: Kinetic parameters: Vmax=9.7 nmol/min/mg enzyme for the hydrolysis of oleamide ((9Z)-octadecenamide) {ECO:0000269|PubMed:17015445}; Vmax=2.1 nmol/min/mg enzyme for the hydrolysis of N-palmitoyl ethanolamine (N-hexadecanoyl ethanolamine) {ECO:0000269|PubMed:17015445}; Vmax=5.6 nmol/min/mg enzyme for the hydrolysis of N-oleoyl ethanolamine (N-(9Z-octadecenoyl)-ethanolamine) {ECO:0000269|PubMed:17015445}; Vmax=17 nmol/min/mg enzyme for the hydrolysis of anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine) {ECO:0000269|PubMed:17015445}; Vmax=0.75 nmol/min/mg enzyme for the hydrolysis of N-oleoyltaurine (N-(9Z-octadecenoyl)-taurine) {ECO:0000269|PubMed:17015445}; |
| Metal Binding | |
| Rhea ID | RHEA:26136; RHEA:26137; RHEA:26506; RHEA:26507; RHEA:26132; RHEA:26133; RHEA:45060; RHEA:45061; RHEA:45064; RHEA:45065; RHEA:62984; RHEA:62985; RHEA:62992; RHEA:62993; RHEA:63148; RHEA:63149; RHEA:62976; RHEA:62977; RHEA:63016; RHEA:63017; RHEA:63008; RHEA:63009; RHEA:63028; RHEA:63029; RHEA:62996; RHEA:62997; RHEA:63000; RHEA:63001; RHEA:63004; RHEA:63005; RHEA:63020; RHEA:63021; RHEA:63052; RHEA:63053; RHEA:63120; RHEA:63121; RHEA:35563; RHEA:35564; RHEA:63124; RHEA:63125; RHEA:63128; RHEA:63129; RHEA:63140; RHEA:63141; RHEA:63144; RHEA:63145; RHEA:63156; RHEA:63157; RHEA:63160; RHEA:63161; RHEA:63164; RHEA:63165; RHEA:51316; RHEA:51318; RHEA:64108; RHEA:64109; RHEA:64116; RHEA:64117 |
| Cross Reference Brenda | 3.5.1.4;3.5.1.99; |