| IED ID | IndEnz0005000449 |
| Enzyme Type ID | lipase000449 |
| Protein Name |
Probable 1-alkyl-2-acetylglycerophosphocholine esterase EC 3.1.1.47 |
| Gene Name | ARB_01751 |
| Organism | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Enzyme Sequence | MLVQGTIICALVANAIASSIPSSFLLPEPSGPFKVQREILELTDWSRKDINSTLPRRLMVSRFNPIPEKHCIRTEDVPTFPPASAKLEDAILQAASGGHWVDGLLAASRIRVCADVKKGYQTDSHGDNHGIPILLFSPGGNTTRLVYSSIAQTISSAGYTVITMDHPHDTDIVEFLNGDIITGGEVTFSNPSVLPFWNDVRVQDTVFVLNQALKTSPHARIGMLGHSFGGSAVLSSMVKDGRISAGINFDGGLWGDAVNTGLGGRKKPQPYLQWGAYTHNRHNDTSWETLWKAMERLHPHAWKKELGIPAGRHNTFSDFPAIIDAGGVREVIGKASIDVLVGDIPAARSLEFIKVYVHDFFQFSLFGKDEGLLRGPSSKYPEVVFLD |
| Enzyme Length | 387 |
| Uniprot Accession Number | D4AZY1 |
| Absorption | |
| Active Site | ACT_SITE 227; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:Q13093; ACT_SITE 250; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:Q13093; ACT_SITE 313; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:Q13093 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H2O = 1-O-alkyl-sn-glycero-3-phosphocholine + acetate + H(+); Xref=Rhea:RHEA:17777, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30089, ChEBI:CHEBI:30909, ChEBI:CHEBI:36707; EC=3.1.1.47; Evidence={ECO:0000250|UniProtKB:Q13093}; |
| DNA Binding | |
| EC Number | 3.1.1.47 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (3); Signal peptide (1) |
| Keywords | Glycoprotein;Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21919205}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 42,265 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:17777 |
| Cross Reference Brenda |