IED ID | IndEnz0005000472 |
Enzyme Type ID | lipase000472 |
Protein Name |
Cholinesterase 1 EC 3.1.1.8 Fragment |
Gene Name | CHE1 |
Organism | Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Cephalochordata Leptocardii Amphioxiformes Branchiostomidae Branchiostoma Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum) |
Enzyme Sequence | TPISEDCLYLNVWQPSPAPTGATVLVWIYGGGFFSGTSSLDVYDGRYLARMEDVVVVSMNYRLGALGFLYTGSEAAPGNAGLLDQHLALQWVQQNIQSFGGDPGKVTIFGESAGAASVNFHMLSPMSRDLFQRAMMHSASALAPWAVTPSEQARQRSKALAIDIGCSADEEDMDVLVACLREVSAQTILDHEWNVVDLSDAHFLADIPFPPVKDGRFITEDPAEMYAAGNFKDIDILVGFVKDEGNFWLVYGVPGFDKDTDSIIDRETFVGDIVFCHPRLNDITVERTAFEYTDWLHMDQDTMYRDALDSVFGDPFFVCPTMAVGKAHVNHGRTAYVYEFAQVASNLAWPHWMGAMH |
Enzyme Length | 357 |
Uniprot Accession Number | Q95000 |
Absorption | |
Active Site | ACT_SITE 112; /note=Acyl-ester intermediate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10039; ACT_SITE 244; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 357; /note=Charge relay system; /evidence=ECO:0000250 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=an acylcholine + H2O = a carboxylate + choline + H(+); Xref=Rhea:RHEA:21964, ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29067, ChEBI:CHEBI:35287; EC=3.1.1.8; |
DNA Binding | |
EC Number | 3.1.1.8 |
Enzyme Function | |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (3); Chain (1); Disulfide bond (1); Non-terminal residue (2) |
Keywords | Disulfide bond;Hydrolase;Serine esterase |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 39,462 |
Kinetics | |
Metal Binding | |
Rhea ID | RHEA:21964 |
Cross Reference Brenda |