| IED ID | IndEnz0005000473 |
| Enzyme Type ID | lipase000473 |
| Protein Name |
Cholinesterase 2 EC 3.1.1.8 Fragment |
| Gene Name | CHE2 |
| Organism | Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Cephalochordata Leptocardii Amphioxiformes Branchiostomidae Branchiostoma Branchiostoma lanceolatum (Common lancelet) (Amphioxus lanceolatum) |
| Enzyme Sequence | QPSPVPVGATVMVWIYGGGFMSGTASLDVYDGRYIAATQGVIVASMNYRTGAMGFLSLGNSEAPGNAGLMDQNLALTWIKENVASFGGDQSKVSIFGESAGAASVSYHLLSPMSKNLFQRAIMESASALSPWALLPDAEAHRRGVELAKAVGCSTDSDIEETIECMRGVPALTISENEWVVWGLCQFPFAPVVDGNFIREHPTVSLQTGNLKQTDVMVGFNNDEGVYFLLYGAPGFSKDTQSLITRDQYLEGIKMSVMGINDISVDALSFQYIDWVNFDQPSMYRDAIDNLSGDYNFICPALSFGKAMASFMGRKTYQYKFVHQASNFPWPKWTGVM |
| Enzyme Length | 337 |
| Uniprot Accession Number | Q95001 |
| Absorption | |
| Active Site | ACT_SITE 99; /note=Acyl-ester intermediate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10039; ACT_SITE 224; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=an acylcholine + H2O = a carboxylate + choline + H(+); Xref=Rhea:RHEA:21964, ChEBI:CHEBI:15354, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29067, ChEBI:CHEBI:35287; EC=3.1.1.8; |
| DNA Binding | |
| EC Number | 3.1.1.8 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Disulfide bond (1); Glycosylation (1); Non-terminal residue (2) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Serine esterase |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 36,738 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | RHEA:21964 |
| Cross Reference Brenda |