IED ID | IndEnz0005000517 |
Enzyme Type ID | lipase000517 |
Protein Name |
Patatin-like phospholipase domain-containing protein NFIA_019760 EC 3.1.1.- |
Gene Name | NFIA_019760 |
Organism | Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Fumigati Aspergillus fischeri Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) (Aspergillus fischerianus) |
Enzyme Sequence | MTSDEKSATRDIYDPNTLPDYDREFIDPDDLRQFEKALNAPEAAPLVALNDWRPVNQRVRKSRRTKPRRSKDETREGVLYTVLKWPFLFTVFAWITVLGFAYTLTRLYIFLYEQFVTWRGKRERLRKELSMQTNYQDWLKAAQALDTYLGNLKWKETDEYAYYDHLTINKVVAQLKQTRKAAETEMQNGRSGLSDPPAVEELCFLLEACVKNNFAGVENPRLYSETYSGTKDLVQEYIDEVHSCIRLVLDSKQISNEDKYQFFKHLDTNFGRTALCLSGGATFAYYHFGVIRALLDNDVLPEIITGTSGGALVAALVATRTDEELKQLLVPALAHRIRACHEGFTTWVRRWWRTGARFDTLDWARQCSWFCRGSTTFREAYERTGRILNVSCVPSDPHSPTILANYLTSPDCVIWSAVLASAAVPGILNPVVLMTKKRDGTLAPYSFGHKWKDGSLRTDIPIKALNLHFNVNFTIVSQVNPHINLFFFNSRGSVGRPVTHRKGRGWRGGFLGSAIEQYIKLDMNKWLRVLRHLELLPRPLGQDWSEIWLQKFSGTITIWPKSIPSDFYHILSDPSPERLARMLHVGKQSAFPKIQFIKNRLKIENAIMQGLQQCSSGGGRVMSPILSRRRQDRAEEHADRMVERLDQSFPERQSDYKDESHYTEVSDSLSATSSRPHTPDARRSSMFEEMRRQSAVFFDDSDMYADEDAVTT |
Enzyme Length | 712 |
Uniprot Accession Number | A1D4C8 |
Absorption | |
Active Site | ACT_SITE 308; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161; ACT_SITE 453; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.1.1.- |
Enzyme Function | FUNCTION: Probable lipid hydrolase. {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (2); Chain (1); Compositional bias (2); Domain (1); Motif (1); Region (2); Transmembrane (1) |
Keywords | Hydrolase;Lipid degradation;Lipid metabolism;Membrane;Reference proteome;Transmembrane;Transmembrane helix |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | MOTIF 306..310; /note=GXSXG; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
Gene Encoded By | |
Mass | 81,915 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |