| IED ID | IndEnz0005000580 |
| Enzyme Type ID | lipase000580 |
| Protein Name |
Isoamyl acetate-hydrolyzing esterase 1 homolog EC 3.1.-.- Hypertrophic agonist-responsive protein B64 |
| Gene Name | Iah1 Harpb64 |
| Organism | Rattus norvegicus (Rat) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Rattus Rattus norvegicus (Rat) |
| Enzyme Sequence | MSLCELAASGSSLLWPRVLLFGDSITQFSFQQGGWGTLLADRLVRKCDVLNRGFSGYNTRWAKIILPRIIRKGAGLENPVAVTIFFGANDSTLKDENPKQHVPLDEYSANLRDMVQYLRSVDIPKERVILITPPPLCEAAWEKECILKGCKLNRLNVAVGEYAKACLQVARDCGTDVLDLWTLMQKDNQDFSSYLSDGLHLSPLGNEFLFFHLWPLLDKKVSSLPRLLPDWKDVEETKPELSLLGDGDH |
| Enzyme Length | 249 |
| Uniprot Accession Number | Q711G3 |
| Absorption | |
| Active Site | ACT_SITE 24; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:P41734; ACT_SITE 197; /note=Proton donor; /evidence=ECO:0000250|UniProtKB:P41734; ACT_SITE 200; /note=Proton acceptor; /evidence=ECO:0000250|UniProtKB:P41734 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.-.- |
| Enzyme Function | FUNCTION: Probable lipase. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Erroneous initiation (1); Modified residue (1); Sequence conflict (1); Site (2) |
| Keywords | Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | MOD_RES 63; /note=N6-succinyllysine; /evidence=ECO:0000250|UniProtKB:Q9DB29 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 28,004 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |