| IED ID | IndEnz0005000629 |
| Enzyme Type ID | lipase000629 |
| Protein Name |
Patatin-like phospholipase domain-containing protein CNE02340 EC 3.1.1.- |
| Gene Name | CNE02340 |
| Organism | Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Basidiomycota Agaricomycotina Tremellomycetes Tremellales (jelly fungi) Cryptococcaceae Cryptococcus Cryptococcus neoformans species complex Cryptococcus neoformans (Filobasidiella neoformans) Cryptococcus neoformans var. neoformans Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565) (Filobasidiella neoformans) |
| Enzyme Sequence | MPPSPPSSAAADQWNIDYVNEDSPLSPRSFSLPPESPQLSTASPIHQRVSRKRQRATSQGLTYNVIRWPLLFFIFFIIYLEFSAYVITRQIVNIFEWLVAWRGYKAKLRKELRKAKTYDEWVNTAKKLDKHLGFDDWKDVEEDSYFDWALVRRVRRTLTRLRAANDTRGLMDALAVCVRANFAGTESVKMYSETFIGTKKAVEAHIKEVAACLDYVRTATDVSLEEKRAFFRAVNKHYGSSALCLSGGASFGYYHFGVIKAFLEADLLPRVITGTSAGGLCAALLCTRTDSELKELLVPELADKITACSDPFTVWFKRFRQTGARFDTIDWARRSMWFTRGSLTFKEAYTKTGRALNISVVPSDRHSPTILLNHLTAPNCLIWSAILASAAVPGILNPVVLMAKDRSGNIKPHNLGGSRFKDGSLREDIPLGSLHTQFNCNFSIVSQTNPHIHLFFFAPRGSVGRPVAHRKGKGWRGGFILSALESYIKLDLSKHFKVIRDLDLMPQILQSDWSGVFLQRFSGDLTLTPRSTIGDWFHILSDPDRPQMKRMLRVGERVAWPALGMVRNRMTVERAILRGRSEVRTALSHDRTSNDPATSLPETNPELTGALDHVPIESDVDAGFVSRSRRARNKTGSKGGDTPEEQLNLAGVFQLDESSKGVRRRKQKKSGMPLVAEPLGELPEVSPTHSPIATESPQRNYTSNFGDSFRHVRAPSLPALSSPFRSIRSNTSSSSNNVQSPSSSQRFRSQLSITRWFGGVSESSSDEEDEDLGGLQSGEATASSGEEGIPTFQLDSAVESHSDRSEDEMLHSGANVKEEYQSEESEGKIPIPGGERVTQEKIDSSMASGERLRPAGGSKGSAKTPPVQDGA |
| Enzyme Length | 871 |
| Uniprot Accession Number | P0CP52 |
| Absorption | |
| Active Site | ACT_SITE 276; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161; ACT_SITE 422; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.1.- |
| Enzyme Function | FUNCTION: Probable lipid hydrolase. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (7); Domain (1); Motif (1); Region (4); Transmembrane (1) |
| Keywords | Hydrolase;Lipid degradation;Lipid metabolism;Membrane;Reference proteome;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 274..278; /note=GXSXG; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
| Gene Encoded By | |
| Mass | 96,720 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |