Detail Information for IndEnz0005000641
IED ID IndEnz0005000641
Enzyme Type ID lipase000641
Protein Name Esterase S
Est-S
EC 3.1.1.1
Carboxylic-ester hydrolase S
Carboxylesterase-S
Gene Name EstS
Organism Drosophila virilis (Fruit fly)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Brachycera Muscomorpha Eremoneura Cyclorrhapha Schizophora Acalyptratae Ephydroidea Drosophilidae (pomace flies) Drosophilinae Drosophilini Drosophila (fruit flies) Drosophila virilis group Drosophila virilis (Fruit fly)
Enzyme Sequence MTQILLPIALLCLFAASTLSNPLLVELPNGELRGRDNGFYYSYESIPYAEPPIDDLCLEEPRPYTERWENTFDATRPPVDCLQWSQLISQPNKLTGSEDCLTVSIYKPKNLTRISFPVVAHIFGGGWSFGAAIDDGVRPFSSSGNVIVVKTTTEWERLGFMSTGDSVIPGNFGLKDQRLAIKWIRNNIARFGGDPHNIILLGFSTGGSSVHLQLMHKEYGQLVKGAISISGTATVPWAVQANARDLAFRYGKLLGCNNPKNSRELKDCLKKTDAEEFVSTLRHLQVFDYVPFGPFGPVVESPEVESPFLTELPLDTIRSGNFAQVPWLASYTPENGIYNAALLLAKDANGKERIEELNTRWNELAPYFLAYPYTLKRSEMNAHSQKLKYQYLGYKNFSVVNYFDVQRLFTNELYKKGIELSLDSHRKHGASPVYAYVYDNPADKSLAQFLAKRSDISLGTGMGDDYYLLMNNPLREPLRADEKIVSWKLVKMVEDFAAHETLVYDDCVFPNNLGKKKFQLVVIGRNYCKQLEVESFARHGVQ
Enzyme Length 542
Uniprot Accession Number Q05487
Absorption
Active Site ACT_SITE 204; /note=Acyl-ester intermediate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10039
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=a carboxylic ester + H2O = a carboxylate + an alcohol + H(+); Xref=Rhea:RHEA:21164, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:29067, ChEBI:CHEBI:30879, ChEBI:CHEBI:33308; EC=3.1.1.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10039};
DNA Binding
EC Number 3.1.1.1
Enzyme Function FUNCTION: Transferred from the ejaculatory bulbs of males to the female genitals upon copulation, plays an important role in the reproductive biology.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Disulfide bond (3); Glycosylation (2); Signal peptide (1)
Keywords Disulfide bond;Glycoprotein;Hydrolase;Secreted;Serine esterase;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..22; /evidence=ECO:0000250
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 61,070
Kinetics
Metal Binding
Rhea ID RHEA:21164
Cross Reference Brenda