| IED ID | IndEnz0005000690 |
| Enzyme Type ID | lipase000690 |
| Protein Name |
Patatin-like phospholipase domain-containing protein AN0408 EC 3.1.1.- |
| Gene Name | AN0408 |
| Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Enzyme Sequence | MEKSAAGDNIDKYSPSSIPDYDTEFLNPDDLRAFEKALTDQDADPLVALNDWRPVYQRVVRRGRGRRKSAAAAPRRTKDETREGVLYTVLKWPFLLFVLGWITFLSVGYALTRIYIFLYEQWVTWRGKRESLRRELYKHENYDDWLHAAQALDEYLGNQRWKKIDEYAYYDHLTIRKLGRQLRTVRMQVEEEMKRGESGSTVVVEELCNLLEACVKANFAGVENPRLYSEAYSGTKDLVQDYIDEVHACVKVITDSRQARNEEKYSHFKHLDTNFGRTALCLSGGATFAYYHFGVVRALLDNEVLPSIITGTSGGALVAALVGTRTDDELKQLLVPALAHKIKACSEGFTTWARRWWRTGARFDTMDWARQCSWFCRGSTTFREAYERTGRILNVSCVPSDPHSPTILANYLTSPNCVIWSAVLASAAVPGILNPVVLMTKKRDGTLAPYSFGHKWKDGSLRTDIPIKALNLHFNVNFTIVSQVNPHINLFFFSSRGAVGRPVTHRKGRGWRGGFLGSAIEQYIKLDLNKWLKVLRHLELLPRPLGQDWSEIWLQKFSGTVTIWPKTVPSDFYHILSDPSPERLARMLRTGQQSTFPKIQFIKNRLKIEYAILEGLHRFSADGESVGATSIQPFPFDNGAAGADQKSNDPREERLNRNFPERSSEYSYDYVKSFSDFSDDPIVSAENSSVDDNYIVPSRQRDAGAEAGVGTGTAERRGSFSSLFNLEEMRRQSAVFFDDPDLYRDGGDL |
| Enzyme Length | 749 |
| Uniprot Accession Number | Q5BGC2 |
| Absorption | |
| Active Site | ACT_SITE 313; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161; ACT_SITE 458; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.1.- |
| Enzyme Function | FUNCTION: Probable lipid hydrolase. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Motif (1); Region (2); Transmembrane (1) |
| Keywords | Hydrolase;Lipid degradation;Lipid metabolism;Membrane;Reference proteome;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 311..315; /note=GXSXG; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
| Gene Encoded By | |
| Mass | 85,251 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |