Detail Information for IndEnz0005000748
IED ID IndEnz0005000748
Enzyme Type ID lipase000748
Protein Name Selenium-binding protein 1
AtSBP1
Gene Name SBP1 At4g14030 dl3055c FCAALL.79
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MATETEVVAPVTVSNGGSKGCCKYGGPGYATPLAAMSGPSEKLIYVTAVYTGTGIDKPDYLATVDVDPSSPSYSSVIHRLPMPFVGDELHHSGWNSCSSCHGDASVDRRYLVLPSLISGRIYAIDTKENPRAPSLYKYVDPKEIADKTGLAFPHTAHCLATGEILVSCLGDEEGNAKGNGFLLLDSDFNIKNRWEKPGHSPLYGYDFWYQPRHKTMISTSWGAPKAFSKGFNLQHVADGLYGSHLHVYSWPGGEIKQLIDLGPTGLLPLEIRFLHDPSKDTGFVGSALSSNMIRFFKNSDETWSHEVVISVKPLKVENWILPEMPGLITDFLISLDDRFIYFVNWLHGDIRQYNIEDPKNPVLTGQIWVGGLLQKGSPVKAVGEDGNTFQFEVPQIKGKSLRGGPQMIQLSLDGKRLYATNSLFSAWDRQFYPEIMEKGSHIIQIDVDTEKGGLTINPDFFVDFGDEPDGPSLAHEMRYPGGDCTSDIWI
Enzyme Length 490
Uniprot Accession Number O23264
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Binds cadmium and mediates lower sensitivity to stress requiring glutathione (GSH) for tolerance (e.g. cadmium, selenate, and hydrogen peroxide excess). Probably helps to detoxify cadmium potentially through direct binding (PubMed:18354042, PubMed:19710230). Binds selenium, cadmium, zinc and nickel in vitro (PubMed:25274629). {ECO:0000269|PubMed:18354042, ECO:0000269|PubMed:19710230, ECO:0000269|PubMed:25274629}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Initiator methionine (1); Modified residue (1); Mutagenesis (1); Sequence conflict (10); Site (2)
Keywords Acetylation;Reference proteome;Selenium
Interact With
Induction INDUCTION: Induced by cadmium (at protein level) (PubMed:16502469, PubMed:18354042, PubMed:19710230). Induced by selenium (selenate), copper and hydrogen peroxide H(2)O(2) (at protein level) (PubMed:16502469, PubMed:18354042, PubMed:19710230). The induction in response to sulfur starvation is repressed by glutathione (GSH) (at protein level) (PubMed:19710230). {ECO:0000269|PubMed:16502469, ECO:0000269|PubMed:18354042, ECO:0000269|PubMed:19710230}.
Subcellular Location
Modified Residue MOD_RES 2; /note=N-acetylalanine; /evidence=ECO:0007744|PubMed:22223895
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 12609038; 12644654; 15208337; 15247402; 16244144; 17828791; 18650403; 28627464; 29574326;
Motif
Gene Encoded By
Mass 54,057
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda