| IED ID | IndEnz0005000753 |
| Enzyme Type ID | lipase000753 |
| Protein Name |
Fatty acyl-CoA hydrolase precursor, medium chain EC 3.1.2.- Thioesterase B |
| Gene Name | |
| Organism | Anas platyrhynchos (Mallard) (Anas boschas) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Archelosauria Archosauria Dinosauria Saurischia Theropoda Coelurosauria Aves Neognathae Galloanserae Anseriformes (ducks geese and swans) Anatidae (waterfowl) Anatinae Anas (ducks) Anas platyrhynchos (Mallard) (Anas boschas) |
| Enzyme Sequence | MATEKNTLLSLILTAGITALVATGQKAEQPEVVTNYGSVRGYQVKVNAAERSVNVFLGLPFAKPPVGPLRFSEPQPPEPWKGVRDAASYPPMCLQDKVLGQYLSDAITNRKEKVRLQISEDCLYLNVYTPVSTEEQEKLPVFVWIHGGGLVSGAASSYDGSALAAFDNVVVVTIQYRLGIAGYFSTGDKHARGNWGYLDQVAALQWIQENIIHFRGDPGSVTIFGESAGGVSVSALVLSPLAKGLFHKAISESGTAVRILFTEQPEEQAQRIAAAAGCEKSSSAALVECLREKTEAEMEQITLKMPPMFISASLDGVFFPKSPRQLLSEKVINAVPYIIGVNNCEFGWILPRMMKFPEFTEGLEKDVARQVLQSTLALSFKGAPSDIVDLVYNEYIGVAENRAQVRDGLLDSIADPLFVFSAVEVARHHRDAGNPVYFYEFQHRPSSAAGVVPEFVKADHADEIAFVFGKPFLAGNATEEEAKLSRTVMKYWTNFARNGNPNGEGLVHWPQYDMDERYLEIDLTQKAAKKLKERKMEFWMQLTEQIMSDRRRKHTDL |
| Enzyme Length | 557 |
| Uniprot Accession Number | Q04791 |
| Absorption | |
| Active Site | ACT_SITE 227; /note=Acyl-ester intermediate; /evidence=ECO:0000255|PROSITE-ProRule:PRU10039; ACT_SITE 345; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 460; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.2.- |
| Enzyme Function | FUNCTION: Fatty acid biosynthesis chain termination and release of the free fatty acid product is achieved by hydrolysis of the thio ester by a thioesterase. This thioesterase may be associated with peroxisome proliferation and may play a role in the production of 3-hydroxy fatty acid diester pheromones. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (1); Glycosylation (1); Signal peptide (1) |
| Keywords | Direct protein sequencing;Disulfide bond;Fatty acid biosynthesis;Fatty acid metabolism;Glycoprotein;Hydrolase;Lipid biosynthesis;Lipid metabolism;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..25; /evidence=ECO:0000269|PubMed:8314791 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 61,637 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |