| IED ID | IndEnz0005000955 |
| Enzyme Type ID | lipase000955 |
| Protein Name |
Patatin-like phospholipase domain-containing protein CIMG_04897 EC 3.1.1.- |
| Gene Name | CIMG_04897 |
| Organism | Coccidioides immitis (strain RS) (Valley fever fungus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Onygenales incertae sedis Coccidioides Coccidioides immitis (Valley fever fungus) Coccidioides immitis (strain RS) (Valley fever fungus) |
| Enzyme Sequence | MTANSSRRRLQMKSPRTDGDEKEEDYGLPDFHTRFINDEDLEEFEKALNAPQALSLIAINDWRPIHRRVRKPGKLPKVPQRTKDETREGVVYTLLKWPFLLFVLSWIVFLGALYILTRLYISLYEHFFAWTGQRQRLRRALHSTVDYQHWKNAAKELDEYLGNDAWKERPQYAYYDNTTVMTVVSQLRQLRAQTEAGGINGKAAAEELCTLLEGCIKTNFAGIENPRLYSETYYGTKDLVQEFIEEAHTSLRLVLTSQQLSDERKQGLFRHLDTNFGRTVLCLSGGATLAYYHFGVIKALLDNDVLPDIISGTSGGALVAALVATRTDEELKKLLVPELAHKIKACQDGITTWAVRCWRTGARFDVMQWAEQCSWFCRGSTTFREAYERTGRVLNVSCVPSDPHSPTILANYLTSPNCVIWSAVLASAAVPGILNPVVLMMKKPDGTLAPYSFGHKWKDGSLRTDIPLKALDVHFNASFSIVSQVNPHISLFFFSSRGSVGRPVTHRKGRGWRGGFLGSALEQYIKLDLNKWLKVMRHLELLPRPLGQDWSEIWLQRFSGTVTIWPKSVLSDLYYILSDPSVQRLARMLHEGQQCTFPKIKFISNRMKIERVIAEGLMKDPEWAGSGRWNNVPFRSRTDQTLPLEENAQQRSASMLADTMSHLRDTGHFREAPTSHPTGSPVRPTSGRRNSLMEEIRRQSAVFFDDTDDTMPSDDEKFPYQGQSSGTKIG |
| Enzyme Length | 730 |
| Uniprot Accession Number | Q1DXR6 |
| Absorption | |
| Active Site | ACT_SITE 314; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161; ACT_SITE 459; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.1.- |
| Enzyme Function | FUNCTION: Probable lipid hydrolase. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (2); Domain (1); Motif (1); Region (2); Transmembrane (1) |
| Keywords | Hydrolase;Lipid degradation;Lipid metabolism;Membrane;Reference proteome;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 312..316; /note=GXSXG; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161 |
| Gene Encoded By | |
| Mass | 83,048 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |