Detail Information for IndEnz0005000955
IED ID IndEnz0005000955
Enzyme Type ID lipase000955
Protein Name Patatin-like phospholipase domain-containing protein CIMG_04897
EC 3.1.1.-
Gene Name CIMG_04897
Organism Coccidioides immitis (strain RS) (Valley fever fungus)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Onygenales incertae sedis Coccidioides Coccidioides immitis (Valley fever fungus) Coccidioides immitis (strain RS) (Valley fever fungus)
Enzyme Sequence MTANSSRRRLQMKSPRTDGDEKEEDYGLPDFHTRFINDEDLEEFEKALNAPQALSLIAINDWRPIHRRVRKPGKLPKVPQRTKDETREGVVYTLLKWPFLLFVLSWIVFLGALYILTRLYISLYEHFFAWTGQRQRLRRALHSTVDYQHWKNAAKELDEYLGNDAWKERPQYAYYDNTTVMTVVSQLRQLRAQTEAGGINGKAAAEELCTLLEGCIKTNFAGIENPRLYSETYYGTKDLVQEFIEEAHTSLRLVLTSQQLSDERKQGLFRHLDTNFGRTVLCLSGGATLAYYHFGVIKALLDNDVLPDIISGTSGGALVAALVATRTDEELKKLLVPELAHKIKACQDGITTWAVRCWRTGARFDVMQWAEQCSWFCRGSTTFREAYERTGRVLNVSCVPSDPHSPTILANYLTSPNCVIWSAVLASAAVPGILNPVVLMMKKPDGTLAPYSFGHKWKDGSLRTDIPLKALDVHFNASFSIVSQVNPHISLFFFSSRGSVGRPVTHRKGRGWRGGFLGSALEQYIKLDLNKWLKVMRHLELLPRPLGQDWSEIWLQRFSGTVTIWPKSVLSDLYYILSDPSVQRLARMLHEGQQCTFPKIKFISNRMKIERVIAEGLMKDPEWAGSGRWNNVPFRSRTDQTLPLEENAQQRSASMLADTMSHLRDTGHFREAPTSHPTGSPVRPTSGRRNSLMEEIRRQSAVFFDDTDDTMPSDDEKFPYQGQSSGTKIG
Enzyme Length 730
Uniprot Accession Number Q1DXR6
Absorption
Active Site ACT_SITE 314; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161; ACT_SITE 459; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.1.1.-
Enzyme Function FUNCTION: Probable lipid hydrolase. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Compositional bias (2); Domain (1); Motif (1); Region (2); Transmembrane (1)
Keywords Hydrolase;Lipid degradation;Lipid metabolism;Membrane;Reference proteome;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif MOTIF 312..316; /note=GXSXG; /evidence=ECO:0000255|PROSITE-ProRule:PRU01161
Gene Encoded By
Mass 83,048
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda