| IED ID | IndEnz0005000976 |
| Enzyme Type ID | lipase000976 |
| Protein Name |
Probable lipase C14C8.15 EC 3.1.1.- |
| Gene Name | SPBC14C8.15 |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota Taphrinomycotina Schizosaccharomycetes Schizosaccharomycetales Schizosaccharomycetaceae Schizosaccharomyces Schizosaccharomyces pombe (Fission yeast) Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
| Enzyme Sequence | MTLNGNIMKYCLEKGEILISFLLIALESMFRICTVILPSPLRNWFYEQSKKVYSYFLPELLVDDNANKLTDARDTIDLCALHGYDLEEHFVRTTDGYLLGLHRVYKKKKGKIEELNYLPPVLFIHGLMMNSESWVCNLKKEDAIPFALVEQGYDVWLGNLRGNKYSIKNIKFSSQNPKFWDFSLDSIAIFDIPSIVKYILSVNSFDSISLVGFSQGAILAFAALSIDTELRNSVRAFIALAPAIAPKKYSGRTVKSIIHANSQLLYLMFGRNSMLGSAVFWQAVLYPPVFAKIVDLFLRFFLSWTGKNISETQKIVAYSHLYSFTSVKCFVHWAQITRRKVLQMYDDSPGFKPSYYTNLNRIARYPIENIRLPITLVYGSNDNMVDIETLKTQLPPLSQCIQIPNYEHLDIIMGDTKKDIVIQQVVEQLNHVIAGDYFESIKEEFGLDTELVDGVMNHTI |
| Enzyme Length | 460 |
| Uniprot Accession Number | O60095 |
| Absorption | |
| Active Site | ACT_SITE 214; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 382; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:P80035; ACT_SITE 408; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:P80035 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.1.- |
| Enzyme Function | FUNCTION: Probable lipase. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (2); Topological domain (2); Transmembrane (1) |
| Keywords | Glycoprotein;Golgi apparatus;Hydrolase;Lipid degradation;Lipid metabolism;Membrane;Reference proteome;Signal-anchor;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Golgi apparatus {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 20473289; 23697806; 25452419; 30726745; 34250083; |
| Motif | |
| Gene Encoded By | |
| Mass | 52,670 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |