Detail Information for IndEnz0005000985
IED ID IndEnz0005000985
Enzyme Type ID lipase000985
Protein Name Neuroligin-4, Y-linked
Neuroligin Y
Gene Name NLGN4Y KIAA0951
Organism Homo sapiens (Human)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human)
Enzyme Sequence MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQYPVVNTNYGKIQGLRTPLPSEILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLDERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDGVTPNDFDFSVSNFVDNLYGYPEGKDTLRETIKFMYTDWADKENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSPTYFYAFYHHCQSEMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLNEIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPANNPKHSKDPHKTGPEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRHPSPQRNTTNDITHIQNEEIMSLQMKQLEHDHECESLQAHDTLRLTCPPDYTLTLRRSPDDIPFMTPNTITMIPNTLMGMQPLHTFKTFSGGQNSTNLPHGHSTTRV
Enzyme Length 816
Uniprot Accession Number Q8NFZ3
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Putative neuronal cell surface protein involved in cell-cell-interactions.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Alternative sequence (5); Chain (1); Disulfide bond (3); Erroneous initiation (1); Glycosylation (2); Modified residue (1); Region (2); Sequence conflict (1); Signal peptide (1); Topological domain (2); Transmembrane (1)
Keywords Alternative splicing;Cell adhesion;Cell junction;Cell membrane;Disulfide bond;Glycoprotein;Membrane;Phosphoprotein;Postsynaptic cell membrane;Reference proteome;Signal;Synapse;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell membrane; Single-pass type I membrane protein. Cell junction, synapse, postsynaptic density membrane {ECO:0000250}.
Modified Residue MOD_RES 712; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q62889
Post Translational Modification
Signal Peptide SIGNAL 1..43; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 10433268; 10433269; 10806096; 11498055; 11604393; 15540461; 16242404; 16624946; 16846852; 17897391; 18812509; 18829961; 21282647; 25378172; 7695896; 7736595; 8576240; 9024696; 9115257; 9221768; 9278515; 9927700;
Motif
Gene Encoded By
Mass 92,021
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda