Detail Information for IndEnz0005000988
IED ID IndEnz0005000988
Enzyme Type ID lipase000988
Protein Name Protein ABHD1
EC 3.1.1.-
Alpha/beta hydrolase domain-containing protein 1
Abhydrolase domain-containing protein 1
Lung alpha/beta hydrolase 1
MmLABH1
Gene Name Abhd1 Labh1
Organism Mus musculus (Mouse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse)
Enzyme Sequence MEYPYTTKMLSSSLSPQNGTWSDTISLLLALGVALYLGYYWACVPQRPRLVAGPQFLAFLEQHCPVTVETFYPTLWCFEGRLQTIFRVLLQSQPVVPYRSEVLQTPDGGQFLLDWAEQPNSTHYPDPTTQPIVLLLPGISGSSQEPYILHLVNQALKDGYRAVVFNNRGCRGEELLTHRAYCASNTEDLETVVKHIKRRYSQAPLLAVGISFGGILVLNYLAQTGKAGGLVAGLTMSACWDSFETVDSLETPLNSLLFNQPLTAGLCRLVARNRKPIEKVLDVDFAIKARTIRQLDERYTSVAFGYKDCAAYYQAASPRTKVDAIHTPVLCLNAADDPFSPVHAFPLQAAQKSPYVALLITARGGHIGFLEGLMPWQHCYMNRVLHQYARAIFQHSVGLPDLGVLTPEDGKS
Enzyme Length 412
Uniprot Accession Number Q9QZC8
Absorption
Active Site ACT_SITE 211; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 337; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 366; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.1.1.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Domain (1); Glycosylation (1); Transmembrane (1)
Keywords Glycoprotein;Hydrolase;Membrane;Reference proteome;Serine esterase;Signal-anchor;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 12466851; 14610273; 19073140; 21267068;
Motif
Gene Encoded By
Mass 45,725
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda