IED ID | IndEnz0005000998 |
Enzyme Type ID | lipase000998 |
Protein Name |
14-3-3-like protein 1 Partitioning defective protein 5 |
Gene Name | par-5 ftt-1 M117.2 |
Organism | Caenorhabditis elegans |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
Enzyme Sequence | MSDTVEELVQRAKLAEQAERYDDMAAAMKKVTEQGQELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTEGSEKKQQLAKEYRVKVEQELNDICQDVLKLLDEFLIVKAGAAESKVFYLKMKGDYYRYLAEVASEDRAAVVEKSQKAYQEALDIAKDKMQPTHPIRLGLALNFSVFYYEILNTPEHACQLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDVGAEDQEQEGNQEAGN |
Enzyme Length | 248 |
Uniprot Accession Number | P41932 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Required to modulate lifespan, in concert with hcf-1, acting redundantly with 14-3-3-like protein ftt-2. {ECO:0000269|PubMed:21909281}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Sequence conflict (1) |
Keywords | Cytoplasm;Nucleus;Reference proteome |
Interact With | G5EC23; Q11184; Q10666; Q21921 |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16777605}. Nucleus {ECO:0000269|PubMed:16777605}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | 11784094; 12529635; 12588843; 14551910; 14675534; 14704431; 15066285; 15489339; 15791247; 16049479; 16580661; 16672054; 16824915; 16845399; 16860373; 17098225; 17704769; 17897480; 18182484; 19123269; 19597959; 19922876; 21110867; 21177967; 22560298; 22634595; 23604319; 23800452; 24957743; 25199833; 25487147; 26009280; 26921457; 26952210; 27506200; 28648843; 30353013; 31216475; 31283754; 9171285; |
Motif | |
Gene Encoded By | |
Mass | 28,191 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |