Detail Information for IndEnz0005001065
IED ID IndEnz0005001065
Enzyme Type ID lipase001065
Protein Name Protein ABHD15
Alpha/beta hydrolase domain-containing protein 15
Abhydrolase domain-containing protein 15
Gene Name ABHD15 UNQ6510/PRO21435
Organism Homo sapiens (Human)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human)
Enzyme Sequence MPPWGAALALILAVLALLGLLGPRLRGPWGRAVGERTLPGAQDRDDGEEADGGGPADQFSDGREPLPGGCSLVCKPSALAQCLLRALRRSEALEAGPRSWFSGPHLQTLCHFVLPVAPGPELAREYLQLADDGLVALDWVVGPCVRGRRITSAGGLPAVLLVIPNAWGRLTRNVLGLCLLALERGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIALSRYATALEDTVDTSRLFRSRSLREFEEALFCHTKSFPISWDTYWDRNDPLRDVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVILESFRALTEFFRTEERIKGLSRHRASFLGGRRRGGALQRREVSSSSNLEEIFNWKRSYTR
Enzyme Length 468
Uniprot Accession Number Q6UXT9
Absorption
Active Site ACT_SITE 360; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 391; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Modified residue (1); Natural variant (1); Region (1); Sequence conflict (1); Signal peptide (1)
Keywords Phosphoprotein;Reference proteome;Secreted;Signal
Interact With O76011; Q5JR59-3; P21673; Q2TAL6; Q15007
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
Modified Residue MOD_RES 434; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:23186163
Post Translational Modification
Signal Peptide SIGNAL 1..23; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 20711500; 29768196; 33257193;
Motif
Gene Encoded By
Mass 51,771
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda