| IED ID | IndEnz0005001076 |
| Enzyme Type ID | lipase001076 |
| Protein Name |
GPI inositol-deacylase EC 3.1.-.- |
| Gene Name | bst1 AO090005000419 |
| Organism | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus oryzae (Yellow koji mold) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Enzyme Sequence | MHRRSSGSPVEDDAEDSLSSRIPPEPSNGPNVVDTPEKSRSQVARTGTSIDLRRDATGASTPRSRNSSMWRTPPSSSMTSNPPDCKSSSVMMPLASQRLPIEASPDHQRRYRPSRLRSPWPCSILTAFTTLVASIFLFFILRSFALRQTGGDGCGVPVMSPTFIRMVGFDTEHTRFASKYNLYLYREGGVDPYSQENLGLNGVPVLFLPGNAGSYRQVRSLAAEASRHYYDVVRHDEDRLNAGTRSLDFFMIDFNEDMAAFHGQTLLDQAEYVNEAVAYILSLYHDPRRSRRDPELPDPSAVVLVGHSMGGIVARTALTMTNYQANSVNTIVTMSAPHAKPPVSFDSDIVQTYKQINDYWREAYSQTWANDNPLWHVTLISIAGGSRDTVVPSDYASISSLVPETHGFTVFTSTIPDVWIGMDHLSITWCDQFRKAIIKSLFEVVDVRRATQTKPRAERMRIFKKWYLTGMETVAERTLPRKGVSGKKFTLLTNQQFDKSGDHGSLEVLFCSVFPLQNGKPATAFSMNMDFSGGTSGSTRLACKNAAEDGIHLPASTPSSKRPYDRVQPFSYLQYDLEDLAEHQFVAVVDKANSPTKGFVLAEFSDSSDSVIRARLGLGSLLSAGLKVRLPANRPMLTELQIPAVHSSLLDYRLKIIRKNHGQQQELFAPLLRQSVADPHESKFFVNVKNVNVNLHGLAPFMPPPLREQATLGGVSFHLWTDPSCDSTIDISLSVDIAGSLGELVMRYRTVFAAFPLLVVALVMRKQFQVYDETGYFITFAEGLDSALRSSLPMLLLAMSLLASSLATSTKLPPTDDPFHWRTNSTESPIDFTKNDLLLGSQDAFFWFLVPIFGLISVGVCLVINYVALALIFLLTSIYGFLRSKSGYIRRDEKGNLPIFSSASPRRRLVNSAILLALVSTVIPYQFAYMVACIVQLATSVRASWHAKEAKSTTHYNFANFAYSIFLLMLWILPINALVLLVWAHNLVVHWFMPFSSHHNVLSIMPFVLLVEAMTTGTMIPRVTTRFKHVTSMLFFFIAIYSAIYGVSYAYLLHHLTNILAAWLVGIYFSASGFSLSRLWRVLEGDEAVQNPASGSHTKKKP |
| Enzyme Length | 1102 |
| Uniprot Accession Number | Q2USI0 |
| Absorption | |
| Active Site | ACT_SITE 308; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.-.- |
| Enzyme Function | FUNCTION: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (2); Erroneous initiation (1); Glycosylation (2); Region (1); Transmembrane (9) |
| Keywords | Endoplasmic reticulum;Glycoprotein;Hydrolase;Membrane;Protein transport;Reference proteome;Transmembrane;Transmembrane helix;Transport |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 122,758 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |