| IED ID | IndEnz0005001078 |
| Enzyme Type ID | lipase001078 |
| Protein Name |
GPI inositol-deacylase EC 3.1.-.- |
| Gene Name | bst1 AN6702 |
| Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Enzyme Sequence | MHRRSSGSSPDADDAEDSLASRSSEPSHGCELPEKPLPEIARTGTSIDLRRDTNGKSTPRSRNSSTWRTLSSATTTWASHDPPRYPAVMITPQRLAIEASPDSPHRSRLARLRSPWSCSILTALTTILACVFLFSIVRSFSALQTGSDGCGVPVMSPTFLRMVGFDTEHTRFASKYNLFLYREEGVDPYNHENLGLNGAPVLFLPGNAGSYRQVRSLAAEASRHYAQVVQHDQERLRAGTRSLDFFMIDFNEDMAAFHGQTLLDQAEYVNEAVAYILSLYHDPRRTRRDADLPDPSSVILIGHSMGGIVARTALTMANYQENSVNTIITMSAPHAKAPVSFDSDIVHTYKQINDYWREAYSQTWANNNPLWHVTLISIAGGSRDTVVPSDYASISSLVPETHGFTVFTSTMPDVWIGVDHLSITWCDQFRKAIIKSLFDVVDVRRASQTKPRAERMRIFKKWYLTGLESVSERMLTRNEPSTLVTLEDHTNTILAQGQRLVLRELGHRTGPNVHLLPVPPQGVSGKKFTLLTDQRLDRTGEQGSLEVLFCSVFPLHNGKASSVFALNMDSSDSSGSTRLACKNAAVDEIHLPASTRTSRNAYDRARPFSYLQYDLEDLAEHQFVAVVDKARVPMKGWAIAEFSDSSDALIKARIGLGGLLSAGLKVRLPANRPMLTEVRIPALYSSLLDYKLRVVRHHQAGDPRELFAPLLRQSIADPHESKFFVNVDKVNVNLHGLAPYMPPPLRQTSQNGVSFQLWTDPTCDSTVDITLTVDIVSSLGELVMRYRTVFAAFPLLVVSLTLRKQFQVYDETGFFITFAEGLDSALRSSMPALLLAMSLLASSLATSTKLPTGDDPFHWATNSTETPIDFTKNDLLLGSQDAFFWFLVPLFGLICVGVCVLLNYVALIVLQILSVVYGLWNSKSGYIRRDEKGYLPVFPAPSPRRRMIKMGVLLVLVSTAIPYQFAYLVACIVQLATCVRAQWHAKETRSTAHYNFANYAYSVFILMLWVLPINILVLLVWAHNLVVHWFMPFSSHHNVLSIMPFIILVETMTTGSMIPRVTTRFKHVTSVLLFCIAVYSAVYGVSYAYISHHLVNILAGWLVSIYFFRSGFSLHRFWKIVEGDETPSTPESGSHMKKKP |
| Enzyme Length | 1140 |
| Uniprot Accession Number | Q5AYC8 |
| Absorption | |
| Active Site | ACT_SITE 304; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.-.- |
| Enzyme Function | FUNCTION: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (2); Erroneous initiation (2); Glycosylation (2); Region (1); Transmembrane (9) |
| Keywords | Endoplasmic reticulum;Glycoprotein;Hydrolase;Membrane;Protein transport;Reference proteome;Transmembrane;Transmembrane helix;Transport |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 127,346 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |