Detail Information for IndEnz0005001142
IED ID IndEnz0005001142
Enzyme Type ID lipase001142
Protein Name Isoamyl acetate-hydrolyzing esterase 1 homolog
EC 3.1.-.-
Gene Name Iah1
Organism Mus musculus (Mouse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse)
Enzyme Sequence MSLCERAASGSALLWPRVLLFGDSITQFSFQQGGWGSLLADRLVRKCDVLNRGFSGYNTRWAKIILPRLIRKGPGMENPVAVTIFFGANDSSLKDENPKQHVPLDEYSANLRDMVQYLRSVDVPRERVILITPPPLCEAAWEKECVLKGCKLNRLNSVVGEYANACLQVARDCGTDVLDLWTLMQKDSQDFSSYLSDGLHLSPMGNEFLFLNLCPLLDKKVSSLPWLLPYWKDVEEAKPELSLLGDGDY
Enzyme Length 249
Uniprot Accession Number Q9DB29
Absorption
Active Site ACT_SITE 24; /note=Nucleophile; /evidence=ECO:0000250|UniProtKB:P41734; ACT_SITE 197; /note=Proton donor; /evidence=ECO:0000250|UniProtKB:P41734; ACT_SITE 200; /note=Proton acceptor; /evidence=ECO:0000250|UniProtKB:P41734
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.1.-.-
Enzyme Function FUNCTION: Probable lipase. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Modified residue (1); Site (2)
Keywords Hydrolase;Lipid degradation;Lipid metabolism;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue MOD_RES 63; /note=N6-succinyllysine; /evidence=ECO:0007744|PubMed:23806337
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 11217851; 14610273; 16615898; 21267068; 27266874; 27626380; 32407372;
Motif
Gene Encoded By
Mass 27,974
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda