Detail Information for IndEnz0005001146
IED ID IndEnz0005001146
Enzyme Type ID lipase001146
Protein Name Lipase maturation factor 2
Gene Name LMF2
Organism Bos taurus (Bovine)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos (oxen cattle) Bos taurus (Bovine)
Enzyme Sequence MAGSRVPRQLFLQGVAAVFMFAFASLYTQIPGLYGPEGILPARRTLRPQGKGRWQQLWETPTLLWEAPLLGLDTAQGLELLSLLGTVLALGALLTRQLHHPLVYLLLWAAYLSVCQVGQVFLYFQWDSLLLETGFLAMLVAPLGLPPNHKQAPQGRPGGVSPHEGLPFWLVRWLLFRLMFASGVVKLTSRCPAWWGLTALTYHYETQCLPTPAAWFAHHLPVWLHKLSVVATFLIEIAVPPLFFAPVRRLRLAAFYSQVLLQVLIILTGNYNFFNLLTLVLTTALLDDTHLAAKSSTSRRKRMPSSWPKALLAMLTLLLELAVYGLLACGVVHYFGLEVDWEQHVVRSRTMFTFHQLSQWLKTVTLPTMWLGAASLAWELLTALWRWVQVRGSLRKLCAAVQLSVFGTATVALFLISLVPYSYMEPSSHGRLWTGAHRLFSTVEHLQLANSYGLFRRMTGLGGRPEVVLEGSYDGHQWTEIEFMYKPGNLSRPPPIVVPHQPRLDWQMWFAALGPHTHSPWFTSLVLRLLQGKEPVIRLVQNHVPSYPFHQQPPTYVRAQLYKYWFSHPWEQGQWWRRQWVEEFFPSVSLGDPALDMLLRQFGLQDKSPPRAGGSSNTLSQALHWVRKQLSPLEAPALLWGLLGAVGAIKVMQALLGPQSLPRTKEEKHKPAPQEDSVAASKQASPAPNISSGSQTPRRKKSP
Enzyme Length 703
Uniprot Accession Number A1L504
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Involved in the maturation of specific proteins in the endoplasmic reticulum. May be required for maturation and transport of active lipoprotein lipase (LPL) through the secretory pathway (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Alternative sequence (2); Chain (1); Compositional bias (1); Frameshift (1); Glycosylation (1); Region (1); Sequence conflict (3); Transmembrane (11)
Keywords Alternative splicing;Endoplasmic reticulum;Glycoprotein;Membrane;Reference proteome;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 79,266
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda