Detail Information for IndEnz0005001160
IED ID IndEnz0005001160
Enzyme Type ID lipase001160
Protein Name Lecithin-cholesterol acyltransferase-like 1
EC 2.3.1.-
Gene Name LCAT1 At1g27480 F17L21.27 F17L21.28
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MKKISSHYSVVIAILVVVTMTSMCQAVGSNVYPLILVPGNGGNQLEVRLDREYKPSSVWCSSWLYPIHKKSGGWFRLWFDAAVLLSPFTRCFSDRMMLYYDPDLDDYQNAPGVQTRVPHFGSTKSLLYLDPRLRDATSYMEHLVKALEKKCGYVNDQTILGAPYDFRYGLAASGHPSRVASQFLQDLKQLVEKTSSENEGKPVILLSHSLGGLFVLHFLNRTTPSWRRKYIKHFVALAAPWGGTISQMKTFASGNTLGVPLVNPLLVRRHQRTSESNQWLLPSTKVFHDRTKPLVVTPQVNYTAYEMDRFFADIGFSQGVVPYKTRVLPLTEELMTPGVPVTCIYGRGVDTPEVLMYGKGGFDKQPEIKYGDGDGTVNLASLAALKVDSLNTVEIDGVSHTSILKDEIALKEIMKQISIINYELANVNAVNE
Enzyme Length 432
Uniprot Accession Number Q9FZI8
Absorption
Active Site ACT_SITE 209; /note=Acyl-ester intermediate; /evidence=ECO:0000255; ACT_SITE 374; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 400; /note=Charge relay system; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 2.3.1.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Transmembrane (1)
Keywords Acyltransferase;Membrane;Reference proteome;Transferase;Transmembrane;Transmembrane helix
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 15247387; 15539469; 16020547; 17151019; 17337630; 18650403;
Motif
Gene Encoded By
Mass 48,308
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda