| IED ID | IndEnz0005001192 |
| Enzyme Type ID | lipase001192 |
| Protein Name |
Antibacterial peptide AN1 Bacteriocin AN1 Fragment |
| Gene Name | |
| Organism | Limosilactobacillus mucosae (Lactobacillus mucosae) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Lactobacillales Lactobacillaceae Limosilactobacillus Limosilactobacillus mucosae (Lactobacillus mucosae) |
| Enzyme Sequence | LVALDTEFANR |
| Enzyme Length | 11 |
| Uniprot Accession Number | C0HL60 |
| Absorption | |
| Active Site | |
| Activity Regulation | ACTIVITY REGULATION: Antimicrobial activity was completely lost after treatment with proteinase k, or high concentrations of chymotrypsin, trypsin or pepsin (PubMed:29064056). Also inhibited by isopropanol, methanol, acetonitrile and chloroform (PubMed:29064056). There was no significant loss of activity with either lipase, peroxidase, or amylase (PubMed:29064056). {ECO:0000269|PubMed:29064056}. |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Has antibacterial activity against L.monocytogenes. {ECO:0000269|PubMed:29064056}. |
| Temperature Dependency | BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Optimum temperature is 30 degrees Celsius. Active from 30 to 100 degrees Celsius. {ECO:0000269|PubMed:29064056}; |
| PH Dependency | BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is about 6. Activity decreases sharply with increasing alkalinity. {ECO:0000269|PubMed:29064056}; |
| Pathway | |
| nucleotide Binding | |
| Features | Non-terminal residue (1); Peptide (1) |
| Keywords | Antibiotic;Antimicrobial;Direct protein sequencing;Secreted |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:29064056}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 1,248 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |