| IED ID | IndEnz0005001197 |
| Enzyme Type ID | lipase001197 |
| Protein Name |
GPI inositol-deacylase EC 3.1.-.- |
| Gene Name | bst1 AFUA_7G05540 |
| Organism | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Fumigati Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Enzyme Sequence | MHRRSSGSPVEDDAEDSPLVSRSPTESTAHGPNNNAFETAEKSRSQIAKRGTSFDLRRDNGASTPRSRNSGLWRTPSSSSTSSTTAMATASTETKSSSASFLMPLASQRLPMGTSPESSRFRSSRLRSPWTCSILTALTTLVASVFLFFIVRSFSARQAGEDGCGIPVMSPTFLHMVGFDTEHTRFASKYNLYLYREEGVDFYNQENLGLNGAPVLFLPGNAGSYRQVRSLAAEASRHFHDVVRHDQERIKAGTRSLDFFMIDFNEDMAAFHGQTLLDQAEYVNEAIAYILSLYHDPKRSRRDPELPDPSSVILIGHSMGGIVARTALTMSNYQANSVNTIVTMSAPHAKPPVSFDSDIVHTYKQINDYWREAYSQTWANNNPLWHVTLISIAGGSRDTVVPSDYASISSLVPETHGFTVFTSSIPDVWIGVDHLSITWCDQFRKAIIKSLFDIIDVRRASQTKPRAERMRIFKKWYLTGLEPVAERTLSQKEPNTLLTLEDKSNSILPQGQRLILRELGHRSGPKVYLLPVPPQGVSGKKFTLLTDQRFDKTGEHGNLEVLFCSVFPLQNGKFATVFSMNMDFSGGNTGSTRLACKNAAEDGIHLPASTPASKYPFDRVQPFSYLQYELEDLSEHQFVAIVDKADSPTKGWVLAEFSDSSDAVIRVRGGLGGLLSAGLKMRLPANRPMLTEIKIPALHSSLLDYKLQIVRHNHDKRQELFAPLLRQSISDPHESKFFVNVDKVDVNLHGVAPFMPPPLREQATLGGVSFQLWTDPSCGSTVDVSLKVDIAGSLGELVMRYRTVFAAFPLLVVALVLRKQFQMYDETGYFITFAEGLDTALRSSFPILLLAMSLLASSLATSAQIPPSDEPFQWPVNATETPIDFTKNDLLLGSQDAFFWFLVPVFGLISVGVCVILNYIALILLSVLSFIYGCLRTRSGYIKRNEKGTPIFSAPTARRRMINTAILLVLVSTLIPYQFAYMVACIVQLATCVRAQWHAKETRSTAHYNFSNYAHSIFILMLWILPINILVLLVWAHNLVVHWFMPFSSHHNVLSIMPFILLVETMTSGAMIPRVTTRLKHVTSMILFAIAVYSAVYGVSYAYLLHHLANILAAWFVVIYFFSSGFSLRRLWLILEGDDATQGKSEPGGSHQKKKP |
| Enzyme Length | 1156 |
| Uniprot Accession Number | Q4WGM4 |
| Absorption | |
| Active Site | ACT_SITE 318; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.-.- |
| Enzyme Function | FUNCTION: Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (3); Glycosylation (2); Region (1); Transmembrane (9) |
| Keywords | Endoplasmic reticulum;Glycoprotein;Hydrolase;Membrane;Protein transport;Reference proteome;Transmembrane;Transmembrane helix;Transport |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 128,763 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |