| IED ID | IndEnz0005001265 |
| Enzyme Type ID | lipase001265 |
| Protein Name |
Inactive GDSL esterase/lipase-like protein 25 GDSL-like lipase 25 Myrosinase-associated protein GLL25 Protein ENDOPLASMIC RETICULUM MORPHOLOGY 3 Protein GOLGI DEFECTS 36 Protein MODIFIED VACUOLE PHENOTYPE 1 Protein NUCLEAR CAGE |
| Gene Name | MVP1 ERMO3 GLL25 GOLD36 NUC At1g54030 F15I1.11 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MLLIPSFTANSNEPPPSKLSLSDLSMAILKSHFFLLFPLLLLHFHTVSFAQTLFVFGDGLYDAGNKQFLSQNRVDASFPPYGVTVGQATGRWSDGSIVPDYLAKFMGIPKISPILLTTADFSHGANFAIADATVLGSPPETMTLSQQVKKFSENKNKWTNQTRSEAIYLIYIGSDDYLSYAKSNPSPSDTQKQAFVDQVITTIKAEIKVVYGSGGRKFAFQNLAPLGCLPAVKQASGNVQECVKLPSEMAALHNKKLLQLLVELSRELNGFQYSFYDFFSSIQNRVIKSKTYTFETGNAACCGTGSINGSNCSAKNVCAKPEEYIFFDGKHLTQEANLQVGHLMWGADPEVIGPNNIRELMVLPLDITVILAGIQEAMAAMRPRQSNIESLYDIKKMESEMDNHWLYQVDKAISFMI |
| Enzyme Length | 417 |
| Uniprot Accession Number | Q7XA74 |
| Absorption | |
| Active Site | ACT_SITE 331; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Involved in organization of the endomembrane system and is required for endoplasmic reticulum morphology and organelle distribution. May act by inhibiting the formation of PYK10 complex by binding to GLL23 and exporting it from the ER. Required for proper subcellular localization of myrosinase TGG2. Has no lipase or esterase activity. {ECO:0000269|PubMed:19880612, ECO:0000269|PubMed:20626647, ECO:0000269|PubMed:23155454, ECO:0000269|PubMed:24330158}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Erroneous gene model prediction (1); Erroneous initiation (1); Glycosylation (3); Mutagenesis (4); Sequence caution (1); Sequence conflict (8); Signal peptide (1) |
| Keywords | Endoplasmic reticulum;Glycoprotein;Reference proteome;Signal;Vacuole |
| Interact With | |
| Induction | INDUCTION: Up-regulated by methyl jasmonate and upon pathogen infection. {ECO:0000269|PubMed:19880612}. |
| Subcellular Location | SUBCELLULAR LOCATION: Vacuole. Endoplasmic reticulum. Note=Also found in ER bodies. Retained in the ER when mutated. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..50; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 15539469; 18400103; 18796151; 21798944; 27247031; 28840447; |
| Motif | |
| Gene Encoded By | |
| Mass | 46,083 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |