| IED ID | IndEnz0005001332 |
| Enzyme Type ID | lipase001332 |
| Protein Name |
GDSL esterase/lipase 2 EC 3.1.1.- Extracellular lipase 2 |
| Gene Name | GLIP2 At1g53940 F15I1.2 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MENSRSTLIIFFAYTTIILIGSINCRDNNNNNLVTNQSALFVFGDSVFDAGNNNYIDTLPSFRSNYWPYGQTTFKFPTGRVSDGRTIPDFIAEYAWLPLIPAYLQPSNGKNQFPYGVSFASAGAGALVGTFPGMVINLKSQLNNFKKVEKLLRSTLGEAQGKMVISRAVYLFHIGVNDYQYPFSTNSSIFQSSPQEIYVDFVVGNTTAVIKEVYKIGGRKFGFLNMGAYDCAPASLIIDQTKIGTCFKPVTELINLHNEKLESGLRRLERELSGFKYALHDYHTSLSVRMNNPSKYGFKEGKMACCGTGPLRGINTCGGRMGVSQSYELCEKVTDYLFFDHFHLTEKAHQQIAELIWSGPTNVTKPYNLQALFELN |
| Enzyme Length | 376 |
| Uniprot Accession Number | Q9SYF0 |
| Absorption | |
| Active Site | ACT_SITE 46; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 340; /evidence=ECO:0000250; ACT_SITE 343; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.1.- |
| Enzyme Function | FUNCTION: Involved in the resistance to the necrotropic bacteria Erwinia carotovora, probably via negative regulation of auxin signaling. Possesses lipase and antimicrobial activities, inhibiting germination of fungal spores (e.g. Alternaria brassicicola). {ECO:0000269|PubMed:19146828}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (4); Signal peptide (1) |
| Keywords | Auxin signaling pathway;Glycoprotein;Hydrolase;Lipid degradation;Lipid metabolism;Plant defense;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | INDUCTION: In roots, by salicylic acid (SA), jasmonic acid (JA), and ethylene (ET) treatments. {ECO:0000269|PubMed:19146828}. |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..25; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 42,014 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |