| IED ID | IndEnz0005001338 |
| Enzyme Type ID | lipase001338 |
| Protein Name |
Zinc finger protein GLIS2 homolog Protein sugarbabe |
| Gene Name | sug CG3850 |
| Organism | Drosophila melanogaster (Fruit fly) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Brachycera Muscomorpha Eremoneura Cyclorrhapha Schizophora Acalyptratae Ephydroidea Drosophilidae (pomace flies) Drosophilinae Drosophilini Drosophila (fruit flies) Sophophora melanogaster group melanogaster subgroup Drosophila melanogaster (Fruit fly) |
| Enzyme Sequence | MDIIQKSIFNSGPHSRGIYEPPLGYFTPYNTPPYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQHIRFPTPPITPPRPIAGYGYRQRTQSVIMKARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCNWTDCDRVFDTLDALAQHVTQRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHLCEKSFSRAENLKIHIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTFKHSIHLIASQPLTLPSVPCLLEASSESAFTCLPAASSVESTSSSSSARYYDDSNNEPSDYSLKPKQDAEFSPSYWLGDRQHSYLHSEDFFVKMDVESPLDLRIHRI |
| Enzyme Length | 384 |
| Uniprot Accession Number | Q7K0S9 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Transcription factor which represses a set of lipase genes involved in fat catabolism. {ECO:0000269|PubMed:12426388}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (1); Region (1); Zinc finger (5) |
| Keywords | DNA-binding;Developmental protein;Metal-binding;Nucleus;Reference proteome;Repeat;Repressor;Transcription;Transcription regulation;Zinc;Zinc-finger |
| Interact With | |
| Induction | INDUCTION: Strongly and rapidly induced in larvae by maltose, trehalose, glucose, fructose or saccharose, but not by lactose or galactose. {ECO:0000269|PubMed:12426388}. |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 14605208; 14749722; 15207846; 15575970; 16054033; 16814731; 17578907; 19018044; 19079254; 19154620; 19573582; 19740772; 20220848; 20371351; 20617173; 20925960; 20980240; 21074052; 21159815; 21278706; 21641546; 21945372; 22430022; 22479193; 22796493; 23071443; 24755363; 24810915; 24865556; 24961800; 25193493; 25312911; 25568052; 25616197; 25748510; 25779349; 26162375; 26173873; 26231660; 26440885; 26550828; 27783936; 27923532; 29084242; 29203701; 29278834; 29440697; 30143789; 30247122; 30995488; 31014246; 31061470; 31722958; 31794428; 31799578; 31851941; 32978973; 33064591; 33369866; 33723074; 34108216; 34634038; |
| Motif | |
| Gene Encoded By | |
| Mass | 44,035 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |