| IED ID | IndEnz0005001343 |
| Enzyme Type ID | lipase001343 |
| Protein Name |
Gibberellin receptor GID1 EC 3.-.-.- Gibberellin-insensitive dwarf protein 1 Protein GIBBERELLIN INSENSITIVE DWARF1 |
| Gene Name | GID1 Os05g0407500 LOC_Os05g33730 OJ1657_H11.10 P0040B10.6 |
| Organism | Oryza sativa subsp. japonica (Rice) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Petrosaviidae commelinids Poales Poaceae BOP clade Oryzoideae Oryzeae Oryzinae Oryza Oryza sativa (Rice) Oryza sativa subsp. japonica (Rice) |
| Enzyme Sequence | MAGSDEVNRNECKTVVPLHTWVLISNFKLSYNILRRADGTFERDLGEYLDRRVPANARPLEGVSSFDHIIDQSVGLEVRIYRAAAEGDAEEGAAAVTRPILEFLTDAPAAEPFPVIIFFHGGSFVHSSASSTIYDSLCRRFVKLSKGVVVSVNYRRAPEHRYPCAYDDGWTALKWVMSQPFMRSGGDAQARVFLSGDSSGGNIAHHVAVRAADEGVKVCGNILLNAMFGGTERTESERRLDGKYFVTLQDRDWYWKAYLPEDADRDHPACNPFGPNGRRLGGLPFAKSLIIVSGLDLTCDRQLAYADALREDGHHVKVVQCENATVGFYLLPNTVHYHEVMEEISDFLNANLYY |
| Enzyme Length | 354 |
| Uniprot Accession Number | Q6L545 |
| Absorption | |
| Active Site | ACT_SITE 198; /evidence=ECO:0000255|PROSITE-ProRule:PRU10038; ACT_SITE 296; /evidence=ECO:0000250|UniProtKB:Q5NUF3 |
| Activity Regulation | |
| Binding Site | BINDING 134; /note="Gibberellin A3"; /evidence="ECO:0000269|PubMed:19037316, ECO:0007744|PDB:3ED1"; BINDING 134; /note="Gibberellin A4"; /evidence="ECO:0000269|PubMed:19037316, ECO:0007744|PDB:3EBL"; BINDING 198; /note="Gibberellin A3"; /evidence="ECO:0000269|PubMed:19037316, ECO:0007744|PDB:3ED1"; BINDING 198; /note="Gibberellin A4"; /evidence="ECO:0000269|PubMed:19037316, ECO:0007744|PDB:3EBL"; BINDING 250; /note="Gibberellin A3"; /evidence="ECO:0000269|PubMed:19037316, ECO:0007744|PDB:3ED1"; BINDING 327; /note="Gibberellin A3; via amide nitrogen"; /evidence="ECO:0000269|PubMed:19037316, ECO:0007744|PDB:3ED1"; BINDING 327; /note="Gibberellin A4; via amide nitrogen"; /evidence="ECO:0000269|PubMed:19037316, ECO:0007744|PDB:3EBL" |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.-.-.- |
| Enzyme Function | FUNCTION: Functions as soluble gibberellin (GA) receptor. GA is an essential hormone that regulates growth and development in plants. Binds with high affinity the biologically active GAs such as GA1, GA3 and GA4, but has low or no affinity for the biologically inactive GAs. Upon GA-binding, it interacts with the DELLA protein SLR1, a repressor of GA signaling. This leads to SLR1 degradation by the proteasome, allowing the GA signaling pathway. {ECO:0000269|PubMed:16193045}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Beta strand (9); Binding site (7); Chain (1); Helix (11); Motif (1); Mutagenesis (2); Region (2); Turn (7) |
| Keywords | 3D-structure;Gibberellin signaling pathway;Hydrolase;Nucleus;Receptor;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16193045}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (2) |
| Cross Reference PDB | 3EBL; 3ED1; |
| Mapped Pubmed ID | 16452510; 16709201; 17080612; 17472566; 17521411; 17644730; 17900970; 17918309; 17965273; 18047669; 18268540; 18506581; 18827181; 19066966; 19369275; 19825540; 20716699; 21098733; 21360613; 22010107; 22429711; 22476293; 23261263; 24463428; 24987490; 25418692; 25511432; |
| Motif | MOTIF 120..122; /note=Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole; /evidence=ECO:0000250|UniProtKB:Q5NUF3 |
| Gene Encoded By | |
| Mass | 39,457 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |