| IED ID | IndEnz0005001374 |
| Enzyme Type ID | lipase001374 |
| Protein Name |
Acetyl-hydrolase EC 3.1.1.- |
| Gene Name | bah |
| Organism | Streptomyces hygroscopicus |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Streptomycetales Streptomycetaceae Streptomyces Streptomyces violaceusniger group Streptomyces hygroscopicus |
| Enzyme Sequence | MASPELELVRELIELNWHTRNGEVEPRRIAYDRAQEAFGNLGVPPGDVVTVGHCTAEWVRPARQDGRTLLYLHGGSYALGSPQSHRHLSSALGDAAGAAVLALHYRRPPESPFPAAVEDAVAAYRMLLEQGCPPGRVTLAGDSAGAGLAVAALQALRDAGTPLPAAAVCISPWADLACEGASHTTRKAREILLDTADLRRMAERYLAGTDPRHPLASPAHGDLTGLPPLLIQVGSEEVLHDDARALEQAALKAGTPVTFEEWPEMFHVWHWYHPVLPEGRRAIEVAGAFLRTATGEGLK |
| Enzyme Length | 299 |
| Uniprot Accession Number | Q01109 |
| Absorption | |
| Active Site | ACT_SITE 143; /evidence="ECO:0000250|UniProtKB:O06350, ECO:0000255|PROSITE-ProRule:PRU10038"; ACT_SITE 237; /evidence="ECO:0000250|UniProtKB:O06350"; ACT_SITE 267; /evidence="ECO:0000250|UniProtKB:O06350" |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.1.1.- |
| Enzyme Function | FUNCTION: This protein removes the N-acetyl group from bialaphos as one of the final steps of the bialaphos biosynthetic pathway. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | PATHWAY: Secondary metabolite biosynthesis; bialaphos biosynthesis. |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Motif (1) |
| Keywords | Antibiotic biosynthesis;Hydrolase |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 73..75; /note=Involved in the stabilization of the negatively charged intermediate by the formation of the oxyanion hole; /evidence=ECO:0000250|UniProtKB:Q5NUF3 |
| Gene Encoded By | |
| Mass | 32,096 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |