Detail Information for IndEnz0005001449
IED ID IndEnz0005001449
Enzyme Type ID lipase001449
Protein Name Bacteriocin BAC79
Fragments
Gene Name
Organism Weissella confusa (Lactobacillus confusus)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Lactobacillales Lactobacillaceae Weissella Weissella confusa (Lactobacillus confusus)
Enzyme Sequence AIAVELARDVFEAIQTLSRGSVFQDMPLVSNKELMDLR
Enzyme Length 38
Uniprot Accession Number C0HLU4
Absorption
Active Site
Activity Regulation ACTIVITY REGULATION: The antimicrobial activity of BAC79 was completely lost after treatment with enzymes trypsin, pepsin, proteinase-K, and carboxypeptidase, while there was no loss of activity with either amylase or lipase. {ECO:0000269|Ref.1}.
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Has antibacterial activity against a wide spectrum of Gram-positive and Gram-negative bacteria, including L.monocytogenes which is inhibited through disruption of the cell membrane. {ECO:0000269|Ref.1}.
Temperature Dependency BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Thermostable. Retains activity up to 100 degrees Celsius, and when exposed to 121 degrees Celsius. Also retains activity after storage at 4 degrees Celsius for 4 months. {ECO:0000269|Ref.1};
PH Dependency BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is between 2 to 4. Active from pH 2 to 6. {ECO:0000269|Ref.1};
Pathway
nucleotide Binding
Features Chain (1); Non-adjacent residues (2); Non-terminal residue (2)
Keywords Antibiotic;Antimicrobial;Bacteriocin;Direct protein sequencing
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 4,264
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda