| IED ID | IndEnz0007000021 |
| Enzyme Type ID | catalase000021 |
| Protein Name |
Catalase-1 EC 1.11.1.6 |
| Gene Name | CAT1 At1g20630 F2D10.11 F5M15.31 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MDPYRVRPSSAHDSPFFTTNSGAPVWNNNSSLTVGTRGPILLEDYHLLEKLANFDRERIPERVVHARGASAKGFFEVTHDITQLTSADFLRGPGVQTPVIVRFSTVIHERGSPETLRDPRGFAVKFYTREGNFDLVGNNFPVFFVRDGMKFPDMVHALKPNPKSHIQENWRILDFFSHHPESLHMFSFLFDDLGIPQDYRHMEGAGVNTYMLINKAGKAHYVKFHWKPTCGIKCLSDEEAIRVGGANHSHATKDLYDSIAAGNYPQWNLFVQVMDPAHEDKFDFDPLDVTKIWPEDILPLQPVGRLVLNKNIDNFFNENEQIAFCPALVVPGIHYSDDKLLQTRIFSYADSQRHRLGPNYLQLPVNAPKCAHHNNHHDGFMNFMHRDEEVNYFPSRLDPVRHAEKYPTTPIVCSGNREKCFIGKENNFKQPGERYRSWDSDRQERFVKRFVEALSEPRVTHEIRSIWISYWSQADKSLGQKLATRLNVRPNF |
| Enzyme Length | 492 |
| Uniprot Accession Number | Q96528 |
| Absorption | |
| Active Site | ACT_SITE 65; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 138; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013}; |
| DNA Binding | |
| EC Number | 1.11.1.6 |
| Enzyme Function | FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Erroneous gene model prediction (2); Metal binding (1); Sequence conflict (5) |
| Keywords | Cytoplasm;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome |
| Interact With | |
| Induction | INDUCTION: By hydrogen peroxide. By abscisic acid (ABA), drought, and salt stress through the MKK1-MPK6 mediation. {ECO:0000269|PubMed:17728292, ECO:0000269|PubMed:18248592}. |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12114563; 12376629; 12938931; 12943550; 14671022; 15608336; 15821981; 16242667; 16247729; 16287169; 16336779; 16502469; 17080932; 17951448; 18230142; 18650403; 18775970; 19017119; 20018591; 20118269; 20637531; 20691023; 20876333; 20947669; 21166475; 21492976; 21665322; 21798944; 22447966; 22525681; 23535337; 23940555; 24018686; 24895758; 26292995; 28391398; 28627464; 29575603; 30291629; 30833711; 31121523; 31384929; 32093294; 32564178; 32595686; 33199020; 9214587; |
| Motif | |
| Gene Encoded By | |
| Mass | 56,762 |
| Kinetics | |
| Metal Binding | METAL 348; /note=Iron (heme axial ligand); /evidence=ECO:0000250 |
| Rhea ID | RHEA:20309 |
| Cross Reference Brenda |