Detail Information for IndEnz0007000034
IED ID IndEnz0007000034
Enzyme Type ID catalase000034
Protein Name Catalase-1
EC 1.11.1.6
Fragments
Gene Name
Organism Comamonas terrigena
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Betaproteobacteria Burkholderiales Comamonadaceae Comamonas Comamonas terrigena
Enzyme Sequence THCLTTAAGAPVARFSTVAGERGAADAERDIRRLFSYGDAARRLGVNHQHIPVNAPR
Enzyme Length 57
Uniprot Accession Number P83657
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013, ECO:0000269|PubMed:12094731, ECO:0000269|PubMed:15177292};
DNA Binding
EC Number 1.11.1.6
Enzyme Function FUNCTION: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. {ECO:0000305}.
Temperature Dependency BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Activity decreases at temperatures above 55 degrees Celsius.;
PH Dependency BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Active from pH 6.0 to 10.0.;
Pathway
nucleotide Binding
Features Chain (1); Metal binding (1); Non-adjacent residues (3); Non-terminal residue (1)
Keywords Direct protein sequencing;Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase
Interact With
Induction INDUCTION: Constitutively expressed. Inducible by oxidative stress in the exponential phase of bacterial growth. {ECO:0000269|PubMed:12094731}.
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 6,099
Kinetics
Metal Binding METAL 37; /note=Iron (heme axial ligand); /evidence=ECO:0000250|UniProtKB:P42321
Rhea ID RHEA:20309
Cross Reference Brenda