| IED ID | IndEnz0007000229 |
| Enzyme Type ID | catalase000229 |
| Protein Name |
Catalase EC 1.11.1.6 |
| Gene Name | cat |
| Organism | Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amphibia Batrachia Anura Neobatrachia Ranoidea Ranidae (riparian frogs) Glandirana Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa) |
| Enzyme Sequence | MADRREKSADQMKLWKESRANQKPDVLTTGGGNPVSDKLNLLTVGPRGPLLVQDVVFTDEMAHFDRERIPERVVHAKGAGAFGYFEVTHDITRYSKAKVFEFIGKRTPIAVRFSTVAGEAGSADTVRDPRGFAVKFYTEDGNWDLTGNNTPIFFVRDAMLFPSFIHSQKRNPQTHMKDPDMVWDFWALRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNAKDEPIYCKFHFKTDQGIRNLTVEEANRLSAEDPDYGIHDLYEAIANGNYPSWTFYIQVMTFEQAERYPFNPFDLTKIWPHKDYPLIPVGKLVLNRNPANYFAEVEQIAFDPSNMPPGIEPSPDKMLQGRLFSYPDTHRHRLGANYLQLPVNCPYKARVANYQRDGPMCFSDNQGGAPNYFPNSFSAPENQPAARESKFRVSADVARYNSSDDDNVSQVRDFYTKVLSEEERKRLCENIAGHLKGAQIFIQKRAVKNFTDVHPDYGNRVQALLDKYNAEGHHKKVIKTYTQHSAHVTANDKANL |
| Enzyme Length | 528 |
| Uniprot Accession Number | Q9PWF7 |
| Absorption | |
| Active Site | ACT_SITE 75; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013; ACT_SITE 148; /evidence=ECO:0000255|PROSITE-ProRule:PRU10013 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.6; Evidence={ECO:0000255|PROSITE-ProRule:PRU10013}; |
| DNA Binding | |
| EC Number | 1.11.1.6 |
| Enzyme Function | FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (1); Initiator methionine (1); Metal binding (1); Region (1) |
| Keywords | Heme;Hydrogen peroxide;Iron;Metal-binding;NADP;Oxidoreductase;Peroxidase;Peroxisome |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Peroxisome {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 60,251 |
| Kinetics | |
| Metal Binding | METAL 358; /note=Iron (heme axial ligand); /evidence=ECO:0000250 |
| Rhea ID | RHEA:20309 |
| Cross Reference Brenda |