Detail Information for IndEnz0007000603
IED ID IndEnz0007000603
Enzyme Type ID catalase000603
Protein Name Catalase-peroxidase
CP
EC 1.11.1.21
Peroxidase/catalase
Gene Name katG DSY1012
Organism Desulfitobacterium hafniense (strain Y51)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Clostridia Eubacteriales Peptococcaceae Desulfitobacterium Desulfitobacterium hafniense (Desulfitobacterium frappieri) Desulfitobacterium hafniense (strain Y51)
Enzyme Sequence MEEKKCPVTGHTQHTPTGGGTKNKDWWPNQLNLNILHQNSALGNPMDPDFNYAEEFKKLDLAAVKKDLYALMTDSQDWWPADYGHYGPLFIRMAWHSAGTYRLNDGRGGAGDGTQRFAPLNSWPDNVNLDKARRLLWPIKQKYGKKISWADLMVLAGNCALESMGFKTFGFAGGREDVWEPQEDIYWGSEGEWLGDQRYSGDRDLENPLAAVQMGLIYVNPEGPNGQPSVLASGRDVRDTFKRMAMNDEETVALVAGGHTFGKCHGAGPASHVGPEPEAAPLEEQGLGWKSTFRSGKGGDTIGSGIEGAWKPNPTTWDMGYLETLFKYDWDLVKSPAGAWQWVPTDPAAADTVQDAHDPAKRHAPMMTTADLSLRMDPIFGPIAKRFRDNPEEFADAFARAWFKLTHRDMGPRSRYLGPEVPEEELIWQDPVPPVDHELIDEQDIADLKAKLLASGLSVSQLVSTAWASASTFRGSDKRGGANGARIRLAPQKDWEINQPAQLAEVLAALEGIQTEFNSSQSGTKKVSLADLIVLGGAAAIEQAARNAGHTLVLPFTPGRTDATQEQTEIYSFAVMEPKADGFRNYLKGKSSAPAEEMLVDRAQLLTLTAPEMTVLLGGLRVLNANYGQSKHGVFTQRPETLTNDFFVNLLDMGTEWKAVSEEKALYEGRDRATGELKWTGTRVDLVFGSNSQLRALAEVYACSDSQDKFLQDFVSAWNKVMNADRFDLA
Enzyme Length 730
Uniprot Accession Number Q24YU1
Absorption
Active Site ACT_SITE 96; /note=Proton acceptor; /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=AH2 + H2O2 = A + 2 H2O; Xref=Rhea:RHEA:30275, ChEBI:CHEBI:13193, ChEBI:CHEBI:15377, ChEBI:CHEBI:16240, ChEBI:CHEBI:17499; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961}; CATALYTIC ACTIVITY: Reaction=2 H2O2 = 2 H2O + O2; Xref=Rhea:RHEA:20309, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240; EC=1.11.1.21; Evidence={ECO:0000255|HAMAP-Rule:MF_01961};
DNA Binding
EC Number 1.11.1.21
Enzyme Function FUNCTION: Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity. {ECO:0000255|HAMAP-Rule:MF_01961}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Compositional bias (1); Cross-link (2); Metal binding (1); Region (1); Site (1)
Keywords Heme;Hydrogen peroxide;Iron;Metal-binding;Oxidoreductase;Peroxidase;Reference proteome
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification PTM: Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme. {ECO:0000255|HAMAP-Rule:MF_01961}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 80,533
Kinetics
Metal Binding METAL 259; /note=Iron (heme b axial ligand); /evidence=ECO:0000255|HAMAP-Rule:MF_01961
Rhea ID RHEA:30275; RHEA:20309
Cross Reference Brenda