| IED ID | IndEnz0007000670 |
| Enzyme Type ID | catalase000670 |
| Protein Name |
GATA-type transcription factor SRE1 Siderophore uptake regulator SRE1 |
| Gene Name | SRE1 COCC4DRAFT_135674 |
| Organism | Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta dothideomyceta Dothideomycetes Pleosporomycetidae Pleosporales Pleosporineae Pleosporaceae Bipolaris Cochliobolus heterostrophus (Southern corn leaf blight fungus) (Bipolaris maydis) Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis) |
| Enzyme Sequence | MAHPSGSGGTSFAPTPTHPHHLSRETSRDELEMAESLRLLNQTHDHQKPRAEATSQEQQQQQQQQQQQQQQQQQQQQQQHAQEDPRSEIYHSLEDAVPIADGPPTPSTAASLQIPNMNYETPNASITGQVCSNCKTTQTPLWRRSPAGETVCNACGLYMKARNQSRPVNLKRNTQTQPTMSVQQSPTPGSTDGSRTCAGNVAGSPRVATYVAADQMAAGTCPGGGRCNGTGGQQGCSGCPAFNNRVSKTAKFALAQANAAPGENRGGSDAASSTSAASASTSAIPACQNCGTTITPLWRRDDAGHIICNACGLYYKLHGTHRPVAMKKQEIKRRKRIVPAADTSSQAPSSVANYSPPQRPSQTPAFEHSVSPDPSTALESREAYTPEPPRGPIAVDFTHYYSNSSVTSNPVALTPTVQPSAPSPRKRSRSATLDPEEPVNPLPHRPNAISAILNPSQTEVDANIDPSLSVPLRTSGGTSPNFTLSPEEKAAKRERLKREAEAMRLELERRQKELEELEND |
| Enzyme Length | 520 |
| Uniprot Accession Number | N4XMB0 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: GATA-type transcription repressor that regulates iron- acquisition genes through specific binding the GATA sequence elements of target promoters (PubMed:23980626). SRE1 targets repressed under iron-replete conditions include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis NPS6, SIDA2 and ABC6, as well as the high-affinity iron permease FTR1, the catalase CAT1, and the superoxide dismutase SOD1 encoding genes (PubMed:23980626). {ECO:0000269|PubMed:23980626}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Coiled coil (1); Compositional bias (6); Region (6); Zinc finger (2) |
| Keywords | Coiled coil;Metal-binding;Nucleus;Repeat;Transcription;Transcription regulation;Zinc;Zinc-finger |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 55,967 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |