| IED ID | IndEnz0007000685 |
| Enzyme Type ID | catalase000685 |
| Protein Name |
Developmental and secondary metabolism regulator VE1 Velvet complex subunit 1 |
| Gene Name | VE1 veA FVEG_09521 |
| Organism | Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Hypocreales Nectriaceae Fusarium Fusarium fujikuroi species complex Gibberella moniliformis (Maize ear and stalk rot fungus) (Fusarium verticillioides) Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) |
| Enzyme Sequence | MATPSSIPAEPKRDVVNRIHRVTRGNRSLWYQMTVLQQPERARACGSGSKANSDRRPVDPPPVVELRIIEGPSVEEGKDITFDYNANFFLYASLEHARPLARGRVNTPAAGNPPILTGVPASGMAYLDRPTEAGYFIFPDLSVRHEGLYILTFSLFETTKEERDFDLEPADGDLPPGVDYRMEIKTDPFSVYSAKKFPGLMESTQLSKTVADQGCPVRIRRDVRMRKRESKPGAGNSNSGGNGFERREEDFGRRRTITPASEDPHSIRNRSHSNSSEQRTPYTDASRRPSMVDAYPPPPPPPPSYEPAPSASRHLDFGDSSAAQYPTPRQYAHQPGLQITPGPPSASYAPTSQSPYSKTDAPYGYVNRNIPPSCPSPAPSLKHELYDRRQSTSTYVPPSPSVYSTEGHHRRDSRPSYPPTPVAAPRPRPMHSQTSLPALKIDQLVSPVSPLPPIEPQTGPAPELPPINVGGKRKHESVFAQSTRPLHNGQRQVDPHYGRSHRGYSPDHDQGWYSRADGQISSVQFNRYYDE |
| Enzyme Length | 531 |
| Uniprot Accession Number | W7MRI4 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (By similarity). The velvet complex hat acts as a global regulator for secondary metabolite gene expression (PubMed:22247572). Controls the expression of the cycotoxins fumonisins and fusarins gene cluster (PubMed:22247572, PubMed:19382792, PubMed:24792348). Involved in cell wall integrity, cell surface hydrophobicity, hyphal polarity and conidiation pattern (PubMed:17054442, PubMed:24792348). Required for pathogenicity against maize seedlings (PubMed:22247572). Involved in oxidative stress resistance by positively regulating the transcription of the catalase-encoding gene CAT2 (PubMed:24792348). {ECO:0000250|UniProtKB:C8VTV4, ECO:0000269|PubMed:17054442, ECO:0000269|PubMed:19382792, ECO:0000269|PubMed:22247572}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (6); Domain (1); Motif (1); Region (3); Sequence conflict (2) |
| Keywords | Cytoplasm;Nucleus;Reference proteome;Sporulation;Transcription;Transcription regulation |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:C8VTV4}. Cytoplasm {ECO:0000250|UniProtKB:C8VTV4}. Note=Enriched in the nucleus in the dark (By similarity). {ECO:0000250|UniProtKB:C8VTV4}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 40..45; /note=Nuclear localization signal; /evidence=ECO:0000250|UniProtKB:C8VTV4 |
| Gene Encoded By | |
| Mass | 58,960 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |