| IED ID | IndEnz0007000701 |
| Enzyme Type ID | catalase000701 |
| Protein Name |
Cell pattern formation-associated protein stuA Stunted protein A |
| Gene Name | stuA AFUA_2G07900 |
| Organism | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Fumigati Neosartorya fumigata (Aspergillus fumigatus) Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
| Enzyme Sequence | MNQTQPYMDVHSSHLSSAQPYASHAATAGAMAHYPQYHQQPPVLQPASTYGPASSYSQYAYPSGVASSQTAPPPPSTSMSSQVPAQLLPLPVNSHTVTAPGYGNTTGTPMQGFVYDTTGQLAPPGAKPRVTATLWEDEGSLCYQVEAKGVCVARREDNHMINGTKLLNVAGMTRGRRDGILKSEKVRHVVKIGPMHLKGVWIPFERALEFANKEKITDLLYPLFVHNIGGLLYHPTNQTRTNMVVQESQQRRLEGPPSARTPQASQPPALHHHHSMQTSIPSQMPQPPTMSSQPGARPPLDRAHTFPTPPASASSLMGLSNQSSSYDWNNQGMNSGVPNTQPLSIDTTLSNTRSMPTTPATTPPGNNLQGMQSYQSQSGYDTSKPYYSTAPPSHPHYAPQYSLSQYGQPMPPHSYIKNEMAPPAGRAPGGQSETETSDVKPADRYSQSNGHVTAGAGESAPEHESEYVQHDNTGYGASRSSYTYTTNTSVGSLAGEHSQLTNDITGSPQQNGSGRMTPRTGGGPPPQWASGYASPRPTAASSLYNIVSDTRGSSNGAGSENYTVASNTAPTYSMGGSLGSGKRGREDDDMGRPDSQGDYESKRRRTNETTVGGPVGGVLLGLQPMKAGGAMPRRR |
| Enzyme Length | 635 |
| Uniprot Accession Number | Q4X228 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | DNA_BIND 163..184; /note=H-T-H motif; /evidence=ECO:0000255|PROSITE-ProRule:PRU00630 |
| EC Number | |
| Enzyme Function | FUNCTION: Transcription factor that regulates asexual reproduction (PubMed:16207816, PubMed:19028996). Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity). Controls the expression of 6 secondary metabolite biosynthetic clusters including 2 involved in the synthesis of alkaloids (fumigaclavine and fumitremorgen), 2 clusters of the ETP class (gliotoxin and an unknown ETP-like toxin), a cluster predicted to produce pseurotin A, and the product of the last cluster is unknown (PubMed:19028996). Controls the production of ergot alkaloids during conidiophore development (PubMed:23925951). Controls expression of sspA and gliP (PubMed:18490465). Involved in the induction of immunoglobulin E-independent mast cell degranulation (PubMed:19527167). {ECO:0000250|UniProtKB:P36011, ECO:0000269|PubMed:16207816, ECO:0000269|PubMed:18490465, ECO:0000269|PubMed:19028996, ECO:0000269|PubMed:19527167, ECO:0000269|PubMed:23925951}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (6); DNA binding (1); Domain (1); Region (5) |
| Keywords | Conidiation;DNA-binding;Reference proteome;Sporulation;Transcription;Transcription regulation |
| Interact With | |
| Induction | INDUCTION: Induced at the onset of developmental competence and highly expressed in competent hyphae (PubMed:16207816). {ECO:0000269|PubMed:16207816}. |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 67,772 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |