| IED ID |
IndEnz0007000718 |
| Enzyme Type ID |
catalase000718 |
| Protein Name |
Velvet complex subunit 2
|
| Gene Name |
VELB FVEG_01498 |
| Organism |
Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Pezizomycotina
leotiomyceta
sordariomyceta
Sordariomycetes
Hypocreomycetidae
Hypocreales
Nectriaceae
Fusarium
Fusarium fujikuroi species complex
Gibberella moniliformis (Maize ear and stalk rot fungus) (Fusarium verticillioides)
Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides)
|
| Enzyme Sequence |
MNSAYHPPDMSQRIPGPAYSSSAPPPIHTYQQHQHPPPPLPPPSQHHHSSHPPLPPPPSAPHPHHQHPPPPPSHSLSSHQHHGQPPHHQPQPYAPAPYQQSQPSQYPRPHPHQQHVPPPSQHDEPPPPPSSGPSPTDHQKDSEYVPPSYSKIEEGSGWKYSLDVKQQPVRARMCGFGDKDRRPITPPPCVRLVIINTETGKEVDYNTLDHAMFVLSVDLWNHDEPGTPSYQQQSLPPSRESGYGQSQGMNYGQDYPPPVQQSYGPAPSYPPSSSYGPPQQYYPRHSGYSAEPSAPPPGAPFRNGYGQDQNALTRMAVVGGQPQGMFTRNLIGSLAASAFRLEDTEGQSGIWFVLQDLSVRTEGTFRLRFSFVNVGRPGGQGTNVNQGRAPILSSCYSESFHVYSAKKFPGVCESTPLSKKFANQGIKIPIRKDANIKGEGDEEMYDQN |
| Enzyme Length |
448 |
| Uniprot Accession Number |
W7LFK5 |
| Absorption |
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| Active Site |
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| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
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| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Component of the velvet transcription factor complex that controls sexual/asexual developmental ratio in response to light, promoting sexual development in the darkness while stimulating asexual sporulation under illumination (PubMed:24792348). The velvet complex acts as a global regulator for secondary metabolite gene expression (By similarity). Component of the VELB-VOS1 heterodimeric complex that plays a dual role in activating genes associated with spore maturation and repressing certain development-associated genes (By similarity). The VELB-VOS1 complex binds DNA through the DNA-binding domain of VOS1 that recognizes an 11-nucleotide consensus sequence 5'-CTGGCCGCGGC-3' consisting of two motifs in the promoters of key developmental regulatory genes (By similarity). Controls the expression of the fumonisins gene cluster (PubMed:24792348). Involved in cell wall integrity, cell surface hydrophobicity, hyphal polarity and conidiation pattern (PubMed:24792348). Involved in oxidative stress resistance by positively regulating the transcription of the catalase-encoding gene CAT2 (PubMed:24792348). {ECO:0000250|UniProtKB:C8VTS4, ECO:0000269|PubMed:24792348}. |
| Temperature Dependency |
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| PH Dependency |
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| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (4); Domain (1); Region (2) |
| Keywords |
Cytoplasm;Nucleus;Reference proteome;Sporulation;Transcription;Transcription regulation |
| Interact With |
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| Induction |
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| Subcellular Location |
SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:C8VTS4}. Cytoplasm {ECO:0000250|UniProtKB:C8VTS4}. Note=Nuclear localization is mediated by VE1 (By similarity). {ECO:0000250|UniProtKB:C8VTS4}. |
| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
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| Gene Encoded By |
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| Mass |
49,370 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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