| IED ID |
IndEnz0008000168 |
| Enzyme Type ID |
cellulase000168 |
| Protein Name |
Protein CELLULOSE SYNTHASE INTERACTIVE 3
|
| Gene Name |
CSI3 At1g77460 T5M16.5 |
| Organism |
Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Viridiplantae
Streptophyta
Streptophytina
Embryophyta
Tracheophyta
Euphyllophyta
Spermatophyta
Magnoliopsida
Mesangiospermae
eudicotyledons
Gunneridae
Pentapetalae
rosids
malvids
Brassicales
Brassicaceae
Camelineae
Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
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| Enzyme Sequence |
MLKAFLPGTQEEETLSSLQSGKVDAKMEMDDPEKAMATVAQLIEQLHAKTSSPQDKELTTARLLGIAKGKREARRLIGSYGQAMPLFISMLRNGTTLAKVNVASILCVLCKDKDLRLKVLLGGCIPPLLSVLKSGTMETRKAAAEAIYEVSSAGISNDHIGMKIFITEGVVPTLWDQLSLKGNQDKVVEGYVTGALRNLCGVDDGYWRLTLEGSGVDIVVSLLSSDNPNSQANAASLLARLVLSFCDSIQKILNSGVVKSLIQLLEQKNDINVRASAADALEALSANSDEAKKCVKDAGGVHALIEAIVAPSKECMQGKHGQSLQEHATGALANVFGGMRHLIIYLGQVSQSPRLTEPIGDVIGALAYALMIFKQPESSENIFDPSVIESILVKLLKPRDTKLIQERILEAMASLYGNSSLSCYLDDAEAKRVLIALITMASADVRERLIICLSGLCHDKVGIWEAIGKREGIQLFISFLGLSSEQHQEYAVEMLKILTAQVDDSKWAVTAAGGIPPLVQLLETGSQKAKEDAACILWNLCCHSEEIRDCVERAGGIPAFLWLLKTGGPNSQETSAKTLVKLVHTADPATINQLLALLLGDDPTSKIQVIEVLGHVLSKASQEDLVHRGCAANKGLRSLVESLTSSREETKEHTASVLADLFSSRQDICGHLATDDIINPWIKLLTNNTQNVAKQVARALDALSRPVKNNNNKKKSYIAEGDIKSLIKLAKNSSIESAENAVSALANLLSDPDIAAEALAEDVVSAFTRILADGSPEGKRNASRALHQLLKNFPVCDVLKGSAQCRFAILSLVDSLKSIDVDSADAFNILEVVALLAKTKSGVNFSYPPWIALAEVPSSLETLVQCLAEGHTLVQDKAIEVLSRLCSDQQFLLSELIVSRPKSMLVLADRIVNASSLEVRVGSTALLLCAAKEKKQLITETLDQSGFLKLLLHALVDMIKHNSTSFSLETEVQTPKGFLEKNVFQDTGSFYFPDPAKILGGTVALWLLCILTSVDAKSKVIVMEAGGLEVLVGKLARYTSSAQAEFEDTEGIWISALLLAIMFQDDNVSFSSTTMRIIPTLAVLLGSDELIDRYFAAHAMASLVCTRNRGINLTIANSGAVSGIINLLGYVESEILNLVALANEFSLVKEPDQVILQHLFEIEDVRLGSTARKSIPLLVDLLRPIPDRPGAPQFAVQILIRIADGSDTNKLLMAEAGAVEALTKYLSLSPQDSTEYAISELLRVLFSNHELRQNEMALSSLNQLIAVLRLGSRSARYSAAGALNELFDAENIRNSEIACQAVQPLMDILGSVSESEQEVALSALIKLSSGNTSNTALLIDVEGSLLENVIKILSSATASEELKINAARLCSVVFSNKNIRTSASASGCMKPLITLMQSERSAAVEAAVFAIKILLDDEQHLELAAAHNIQELLVGLVSGKNYVIIEASLSALIKLGKDRVPRKLDMVEAGIIERCLELLPGASSSLCSAVVELFRILTNSGVIARRPDVAKTVEPLFAVLLRSDLTLWGQHSALQALVNILEKQQTLEAFSFTPSEAIVPLISFLESSSQAIQQLGAELLSHFLTMEDFQQDITTQSAVVPLVRLAGIGILSLQETAIKALEKISASWPKAVLDAEGIFELSKVILQEDPQPPLDLWESAAFVLSNILQYDAECFFRVELPVLVKLLFSTIESTVLLALKALMLHEKNDASSTVQMAELGAIDALLDLLRSHQCEEESGSLLEVIFNNPRVRELKLCKYAIAPLSQYLLDPHTRSEPGRLLAALALGDLSQHEGLSRSSGSVSACRALISVLEEQPTEEMKVVAICALQNFVMNSRTNRRAVAEAGGVLLIQELLLSCNPEVSGQAALMVKFLFSNHTLQEYVSNELIRSLTAALERGLWSTATINIEVLRTLNVIFSNFPKLRASEAATFCIPHLVGALKSGVEDVQGLVLDILYLLRHSWTNMSIDVAKSQAMIAAEAIPVLQMLMKTCPPRFHDKADSLLHCLPGCLTVNVMRANNLKQSMATTNAFCQLTIGNCPPRQTKVVSNSTTPEWKEGFTWAFDVPPKGQKLHIICKSKSTFGKTTLGRVTIQIDKVVTEGEYSGSLSLNHENSKDASSRSLDIEIAWSNRTTDETH |
| Enzyme Length |
2136 |
| Uniprot Accession Number |
F4I718 |
| Absorption |
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| Active Site |
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| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
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| catalytic Activity |
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| DNA Binding |
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| EC Number |
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| Enzyme Function |
FUNCTION: Regulator of the microtubular cytoskeleton (By similarity). Microtubule-associated protein involved in the association of cellulase synthase (CESA) complexes (CSCs) and cortical microtubules. Promotes dynamics of CSCs in the plasma membrane in both microtubules-dependent and microtubules-independent manners. Regulates primary cell wall biosynthesis and cellulose microfibrils organization (PubMed:24368796). {ECO:0000250|UniProtKB:F4IIM1, ECO:0000269|PubMed:24368796}. |
| Temperature Dependency |
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| PH Dependency |
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| Pathway |
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| nucleotide Binding |
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| Features |
Chain (1); Domain (1); Erroneous gene model prediction (1); Erroneous initiation (1); Repeat (42); Sequence conflict (1) |
| Keywords |
Cell membrane;Cell shape;Cell wall biogenesis/degradation;Cytoplasm;Cytoskeleton;Developmental protein;Growth regulation;Membrane;Reference proteome;Repeat |
| Interact With |
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| Induction |
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| Subcellular Location |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:24368796}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:F4IIM1}. Endomembrane system {ECO:0000269|PubMed:24368796}. Cytoplasm, cytoskeleton {ECO:0000269|PubMed:24368796}. Note=Colocalizes with cellulase synthase (CESA) complexes (CSCs) in a CSI1-dependent dynamic way. Present with cortical microtubules. {ECO:0000269|PubMed:24368796}. |
| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
12946625;
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| Motif |
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| Gene Encoded By |
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| Mass |
231,432 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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