| IED ID |
IndEnz0008000225 |
| Enzyme Type ID |
cellulase000225 |
| Protein Name |
Protein CELLULOSE SYNTHASE INTERACTIVE 2
|
| Gene Name |
CSI2 At1g44120 T7O23.25 |
| Organism |
Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Viridiplantae
Streptophyta
Streptophytina
Embryophyta
Tracheophyta
Euphyllophyta
Spermatophyta
Magnoliopsida
Mesangiospermae
eudicotyledons
Gunneridae
Pentapetalae
rosids
malvids
Brassicales
Brassicaceae
Camelineae
Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
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| Enzyme Sequence |
MTSEMDDPEKAAVTITRLIEQLHAKKSSAQEKELSTARLLGLAKGKKECRKIISQNVNAMPAFISLLRSGTLLAKLNSASVLTVLCKDKNVRSKILIGGCIPPLLSLLKSDSVDAKRVVAEAIYEVSLCGMDGDNVGTKIFVTEGVVPSLWDQLKTGKKQDKTVEGHLVGALRNLCGDKDGFWALTLEDGGVDIILKLLQSSNPVSQSNAASLLARLIRIFTSSISKVEESGAVQVLVQLLGEENSVFVRASVVNALEAITSKSEEAITVARDLDGIHLLISAVVASSKESVEEETERVLQSYGTQALANLCGGMSGLIVYLGGLSLSPRLTEPIADILGALAYALRKFQLSCGDTREAFDPTLTEGILVKLLKPRDTQLIHERILEAMESLFGNVDLSKLLNNVDAKRVLVCLTILATDGPRERMITCLSNLCKHGDVWDAIGKREGIQILIPYLGLSSEQHQELSVEFLAILTDNVEESRWAVTSAGGIPPLLQILETGVSQKAKDDAVRVILNLCCHSEEIRLCVEKAGAIPALLGLLKNGGPKSQESSANTLLKLIKTADPSVIEQVQALFLGDAPKSKTHLIRVLGHVLASASLEEFVTKGSAANNGLRSLVQRLASSNEKMKENAASVLADLFSSRKDLCGGLGFDEDDNPCTKLLSGNTHAVATQLAHALGSLSNPTKKKTATKKLSGPEVEVIKPLIKSAKTNPIESTENPMSTLANLLSDPNVAAEALNDDVVSALTRVLREGTLQGKRNASHALHQLLKHFQVSDVFKGNEQCRFAVSELIDLLNATDLNNSAFIDVLEVLSLLAKAKYGANLSHNPFSAFGEVPSNLDSLVRGLAEGHPLVQDKAIEILSRFCKTQFILLGRLLVTQSKSISSLANRTINSSSPEIKVGGAILLVCAAKNDITLWAEAVEQSGYLKTLVNTLLDMSKQNSKSASYGIEIQRPRSFITSNLCLRMDDSEMVDPVTILGSTASMWLLSIICSSHPSNRLVVMEGNGLEIIAENLQRNKSNTQENSSDSEEKWIAMSFLAVMSQEPKVVSSPATENILQTLAPFMQSEQMIDGYFTAQVLAALVRHKNDKTISEIMNSDIVETTINLVGCEESDTRSLCALAEELSLVQNPYEATLEVLFENERVRSGSFTKKCIPLLVNLLKPYADKVGGIPVAIRLLRRIADNDDLSKLLIAEAGALDALAKYLSLSPQDSTEITVSELLESLFRSPEITRHKTAISSMKQLIGILHLASRSTRYNAARVLCELFSSEHIRDSELAWKALSPLIEMLNTTLESERVAALTALVKLTMGINPRPDILTSLEGNPLDNIYKILSLDSSSLESKTSAARICRFLFTNEGLRTSTSAACCIVSLISLIRTGKSTAIEAGMFALDRLLDIKRFVEVAEEHDCVNLFYGYVASENYLISEAAISCLTKMAKDNTPRKMDLIKMGIIEKCISQLSKSPPSSLCSVIADLFRVLTNVGVIARSQDAIKMVQPLLLILLRQDLDFQGQLGGLQAIANILEKPMVLESLKIASSTIIMPLIPLLESESIAVKNATTILLTSLLEMQRFQEEITTKNLIAPLVKLVGIRVRNLQEIALMGLERSSVTWPKEVADTGGIQELSKVIIDEDPQLPVYLWESAAFILCNILRINPEHYYFTVTIPVLSKMLFSTAESTVILAIDALIIRENQDSSSVQEMAESSALDALLDLLRSHHCEELSARLLELILRNPKVRETKICQFVLTPLSEYILDPDTISESAKILIAMALGDISQHEGLAKATDSPVACRALISLLEDEPSEEMQMVVMRALENFAMHSRTSRKAMAEAGGVYWVQEMLRSSNPQVSTQAALIIKSLFSNHTLQEYVSGEIIKSLTNAMEREFWTTTAINVEIVRTLNTILTTFPKLRSSEAATACIPHLIGALKSGEQEARDSAMDTIYTLRQSWTTMPTETARSQAVLAADAIPVLQLMMKSKLKSPAPSSFHERGNSLLNCLPGSLTVAIKRGDNLKRSNAFCRLIIDNCPTKKTKVVKRSSSPVWKESFTWDFAAPPRGQFLEIVCKSNNIFRNKNLGKVRIPIDKVLSEGSYSGIFKLNDESKKDNSSDRSLEIEIVWSNQSF |
| Enzyme Length |
2114 |
| Uniprot Accession Number |
Q9C6Y4 |
| Absorption |
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| Active Site |
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| Activity Regulation |
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| Binding Site |
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| Calcium Binding |
|
| catalytic Activity |
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| DNA Binding |
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| EC Number |
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| Enzyme Function |
FUNCTION: Regulator of the microtubular cytoskeleton. Microtubule-associated protein involved in the association of cellulase synthase (CESA) complexes (CSCs) and cortical microtubules. Promotes dynamics of CSCs in the plasma membrane. Regulates primary cell wall biosynthesis and cellulose microfibrils organization. {ECO:0000250|UniProtKB:F4IIM1}. |
| Temperature Dependency |
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| PH Dependency |
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| Pathway |
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| nucleotide Binding |
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| Features |
Chain (1); Domain (1); Repeat (42) |
| Keywords |
Cell membrane;Cell shape;Cell wall biogenesis/degradation;Cytoplasm;Cytoskeleton;Developmental protein;Growth regulation;Membrane;Reference proteome;Repeat |
| Interact With |
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| Induction |
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| Subcellular Location |
SUBCELLULAR LOCATION: Cell membrane {ECO:0000250|UniProtKB:F4IIM1}; Peripheral membrane protein {ECO:0000305}; Cytoplasmic side {ECO:0000305}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:F4IIM1}. Note=Colocalizes with cellulase synthase (CESA) complexes (CSCs) in a dynamic way. {ECO:0000250|UniProtKB:F4IIM1}. |
| Modified Residue |
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| Post Translational Modification |
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| Signal Peptide |
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| Structure 3D |
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| Cross Reference PDB |
- |
| Mapped Pubmed ID |
12946625;
18775970;
24368796;
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| Motif |
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| Gene Encoded By |
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| Mass |
230,854 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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