Detail Information for IndEnz0008000257
IED ID IndEnz0008000257
Enzyme Type ID cellulase000257
Protein Name Glucan 1,3-beta-glucosidase 2
EC 3.2.1.58
Exo-1,3-beta-glucanase 2
Gene Name EXG2 CAALFM_C102630CA CaO19.10469 CaO19.2952
Organism Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Debaryomycetaceae Candida/Lodderomyces clade Candida Candida albicans (Yeast) Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
Enzyme Sequence MMLFLIHLMALCCMFVAEVACEQFNSTSNSSSAQSSLIDFQYKGVSIGGWLVLEPYITPSLFNATLSSGETWTDLPVDEYHFCEKLGAKEAEKRLTDHWESMYNETDFKQIKEAGLNMVRIPIGYWSFEKLEGDPYVSGAQDYLDKAIEWSHANDLKVMIDLHGAPNTQNGFDNSGLRNLGYPGWQNKTEYVNHTYKVLQQMFQKYGTGKYASDYKNTIIGIEVLNEPLNPNMDKLKEFYIESYNDGREIQVINNTIFFQEAFQPIGYWDSFLEKGEIKVTETSNGTNHTTTKKADFKNIIIDHHHYEVFTESQVASNVSTHLENIKNYASAIGKEKAKAIVGEWSAALTDCAPWLNGVGLGSRYEGTAPYTNDRVGSCAEFNKSPDKWSKKQKKDYRRFVEMQLYEYSTNSQGWIFWCWKTEGATEWDFRALVKNGIMPQPLDNYKYVKNGTDTSSASAIASNKMTLLLAFLLVILVI
Enzyme Length 479
Uniprot Accession Number Q5AIA1
Absorption
Active Site ACT_SITE 227; /note=Proton donor; /evidence=ECO:0000250; ACT_SITE 306; /note=Nucleophile; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.; EC=3.2.1.58;
DNA Binding
EC Number 3.2.1.58
Enzyme Function FUNCTION: Beta-glucanases participate in the metabolism of beta-glucan, the main structural component of the cell wall. EXG2 is not heavily involved in the exoglucanase function of the adhesion process. {ECO:0000269|PubMed:21713010}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Glycosylation (11); Lipidation (1); Propeptide (1); Signal peptide (1)
Keywords Cell membrane;Cell wall biogenesis/degradation;GPI-anchor;Glycoprotein;Glycosidase;Hydrolase;Lipoprotein;Membrane;Reference proteome;Secreted;Signal
Interact With
Induction INDUCTION: Induced during cell wall regeneration and repressed by HAP43. {ECO:0000269|PubMed:16455273, ECO:0000269|PubMed:21592964}.
Subcellular Location SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
Modified Residue
Post Translational Modification PTM: Predicted to be a substrate for cleavage by KEX2.
Signal Peptide SIGNAL 1..21; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 54,534
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda