| IED ID | IndEnz0008000329 |
| Enzyme Type ID | cellulase000329 |
| Protein Name |
Endoglucanase-1 EC 3.2.1.4 Cellulase Endo-1,4-beta-glucanase Endoglucanase I FI-CMCase |
| Gene Name | |
| Organism | Aspergillus aculeatus |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus aculeatus |
| Enzyme Sequence | MKAFHLLAALAGAAVAQQAQLCDQYATYTGGVYTINNNLWGKDAGSGSQCTTVNSASSAGTSWSTKWNWSGGENSVKSYANSGLTFNKKLVSQISQIPTTARWSYDNTGIRADVAYDLFTAADINHVTWSGDYELMIWLARYGGVQPIGSQIATATVDGQTWELWYGANGSQKTYSFVAPTPITSFQGDVNDFFKYLTQNHGFPASSQYLITLQFGTEPFTGGPATLSVSNWSASVQ |
| Enzyme Length | 237 |
| Uniprot Accession Number | P22669 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4; |
| DNA Binding | |
| EC Number | 3.2.1.4 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (13); Chain (1); Helix (4); Modified residue (1); Signal peptide (1) |
| Keywords | 3D-structure;Carbohydrate metabolism;Cellulose degradation;Direct protein sequencing;Glycosidase;Hydrolase;Polysaccharide degradation;Pyrrolidone carboxylic acid;Secreted;Signal |
| Interact With | |
| Induction | INDUCTION: By cellulosic materials and hemicelluloses. |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
| Modified Residue | MOD_RES 17; /note=Pyrrolidone carboxylic acid; /evidence=ECO:0000269|PubMed:2249253 |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..16; /evidence=ECO:0000255 |
| Structure 3D | X-ray crystallography (3) |
| Cross Reference PDB | 5GM3; 5GM4; 5GM5; |
| Mapped Pubmed ID | 27470581; |
| Motif | |
| Gene Encoded By | |
| Mass | 25,560 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |