| IED ID | IndEnz0008000351 |
| Enzyme Type ID | cellulase000351 |
| Protein Name |
Exoglucanase 1 EC 3.2.1.91 1,4-beta-cellobiohydrolase I Beta-glucancellobiohydrolase I Exocellobiohydrolase I Exoglucanase I |
| Gene Name | CBH-1 |
| Organism | Cryphonectria parasitica (Chestnut blight fungus) (Endothia parasitica) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Sordariomycetidae Diaporthales Cryphonectriaceae Cryphonectria-Endothia species complex Cryphonectria Cryphonectria parasitica (Chestnut blight fungus) (Endothia parasitica) |
| Enzyme Sequence | MFSKFALTGSLLAGAVNAQGVGTQQTETHPQMTWQSCTSPSSCTTNQGEVVIDSNWRWVHDKDGYVNCYTGNTWNTTLCPDDKTCAANCVLDGADYSSTYGITTSGNALSLQFVTQSSGKNIGSRTYLMESSTKYHLFDLIGNEFAFDVDLSKLPCGLNGALYFVTMDADGGMAKYSTNTAGAEYGTGYCDSQCPRDLKFINGQGNVEGWTPSTNDANAGVGGLGSCCSEMDVWEANSMDMAYTPHPCETAAQHSCNADECGGTYSSSRYAGDCDPDGCDWNPFRMGNKDFYGSGDTVDTSQKFTVVTQFHGSGSSLTEISQYYIQGGTKIQQPNSTWPTLTGYNSITDDFCKAQKVEFNDTDVFSEKGGLAQMGAGMADGMVLVMSLWDDHYANMLWLDSTYPVDADASSPGKQRGTCATTSGVPADVESSDASATVIYSNIKFGPIGATY |
| Enzyme Length | 452 |
| Uniprot Accession Number | Q00548 |
| Absorption | |
| Active Site | ACT_SITE 230; /note=Nucleophile; /evidence=ECO:0000250; ACT_SITE 235; /note=Proton donor; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.; EC=3.2.1.91; |
| DNA Binding | |
| EC Number | 3.2.1.91 |
| Enzyme Function | FUNCTION: The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the disaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Glycosylation (3); Signal peptide (1) |
| Keywords | Carbohydrate metabolism;Cellulose degradation;Glycoprotein;Glycosidase;Hydrolase;Polysaccharide degradation;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 48,358 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |