| IED ID | IndEnz0008000411 |
| Enzyme Type ID | cellulase000411 |
| Protein Name |
Sorbicillinoid biosynthetic cluster transcription factor sor3 Sorbicillinoid biosynthetic cluster protein 3 |
| Gene Name | sor3 ypr2 TRIREDRAFT_102497 |
| Organism | Hypocrea jecorina (strain QM6a) (Trichoderma reesei) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Hypocreales Hypocreaceae Trichoderma Hypocrea jecorina (Trichoderma reesei) Hypocrea jecorina (strain QM6a) (Trichoderma reesei) |
| Enzyme Sequence | MSARQDEDQRLQAQTQAQAQVQAQAPLSLYRERLKIANACQSCRASKVKCDGGRPVCARCQKRGRACSYSQHDAASPRGRGRQRAKAPTRQPRPIRSRASVELPVTAPTPVTAQASPLIAQDYSLQTPSATQTPSTTGFSGSSDLEHVHEDRDESRAFYAAHGRFAGEVSSTIDKMAGLSPDTTCSLVPFVDAPLFGDVGEPPRNVVLDFASDLPRAYADRLLAIYWHHVHPVEPVLDQQQFCRTYDAFYSGSGTPLHVDRDIWLSTLNIVFALAVQIQESIPMQKRDDEANRYFQRAWALLRPEAILWKPGSLELVQCLLLMNRYLHCTNNQQKTSMAATLAIRIAQNMVCHTSEESPSSDADKDLRHKVWASCVALERPALLTGHGSDFHAWELELHEIGTHIQLAQVQSKNSMATKLGLPRLYQQDEYHAIAVQLDGCLNKWEKSLPDDWRLQNMHMIHDRRARAERYLLHFRLLHSRIYLHRPMLARLYAIKSHAPTAAAASDPSTISDRLLQECARMCLEAAQKLTSLIAEIHDPNEPIGILPWWYRVYYLHIAGIHFLAAMFASDLFTPSVERAWYQVLAALRAHEHLSLYVQQCARTFETLAARILNARCLSVNGNGIMALDDGAPGLFLDDMFQDVNFDLDEFLFSVDDTGRRTNY |
| Enzyme Length | 664 |
| Uniprot Accession Number | G0R6T2 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | DNA_BIND 40..67; /note=Zn(2)-C6 fungal-type; /evidence=ECO:0000255|PROSITE-ProRule:PRU00227 |
| EC Number | |
| Enzyme Function | FUNCTION: Transcription factor that acts in concert with sor4 which is a transcriptional activator of the gene cluster that mediates the biosynthesis of sorbicillinoids, a diverse group of yellow secondary metabolites that restrict growth of competing pathogenic fungi but not of bacteria (PubMed:29104566, PubMed:28809958). Regulates the cluster genes in a light dependent manner (PubMed:28809958). Plays also a direct or indirect role in regulation of paracelsin biosynthesis and cellulase gene expression (PubMed:28809958). {ECO:0000269|PubMed:28809958, ECO:0000269|PubMed:29104566}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); DNA binding (1); Region (1) |
| Keywords | DNA-binding;Metal-binding;Nucleus;Reference proteome;Transcription;Transcription regulation;Zinc |
| Interact With | |
| Induction | INDUCTION: The promoter contains putative CRE1 binding motifs 5'-SYGGRG-3' and expression is differentially regulated in light and darkness by CRE1 (PubMed:28809958). Photoreceptors BLR1 and BLR2 negatively regulate the expression, while ENV1 exerts positive regulation (PubMed:28809958). {ECO:0000269|PubMed:28809958}. |
| Subcellular Location | SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 74,747 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |